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Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment
- Jeon, Ok Hee;
- Kim, Chaekyu;
- Laberge, Remi-Martin;
- Demaria, Marco;
- Rathod, Sona;
- Vasserot, Alain P;
- Chung, Jae Wook;
- Kim, Do Hun;
- Poon, Yan;
- David, Nathaniel;
- Baker, Darren J;
- van Deursen, Jan M;
- Campisi, Judith;
- Elisseeff, Jennifer H
Published Web Location
https://doi.org/10.1038/nm.4324Abstract
Pharmacological or genetic depletion of senescent cells in the joint ameliorates osteoarthritis in mice.
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