Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells

2015

et al.

Published Web Location

https://doi.org/10.1038/nature15260

Abstract

Single-cell analysis of gene expression in metastatic cells from distinct human breast tumour models shows that early metastatic cells possess basal, stem and mesenchymal cell properties, whereas advanced metastatic cells have more proliferative properties and are more mature, enabling them to be targeted with an anti-proliferative compound.

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Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells

Published Web Location