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Functional genomic screen identifies novel mediators of collagen uptake

Published Web Location

http://europepmc.org/articles/PMC3937085?pdf=render
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Abstract

Tissue fibrosis occurs when matrix production outpaces matrix degradation. Degradation of collagen, the main component of fibrotic tissue, is mediated through an ex tracellular proteolytic pathway and intracellular pathway of cellular uptake and lysosomal

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