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Adult Stem-Like Cells Exclude “Older” Mitochondria
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https://doi.org/10.1016/j.cmet.2015.04.023Abstract
Asymmetric distribution of damaged cellular constituents may occur during mitosis, resulting in more and less pristine daughter cell pairs. In Science, Katajisto et al., (2015) report that mammary stem-like cells (SLCs) unequally apportion older mitochondria to post-division daughter cells, with the daughter containing younger mitochondria maintaining the SLC pool.
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