UCSF

Clinical evaluation of socket preservation using Platelet Rich Fibrin in comparison with Freeze Dried Allograft: A Randomized Clinical Trial

Yogalakshmi Rajendran, BDS

ABSTRACT

Background: The primary objective of this study was to evaluate the clinical efficiency of Platelet Rich Fibrin (PRF) alone or PRF combined with freeze-dried bone allograft (FDBA) as compared to FDBA alone or no graft (blood clot) in improving alveolar dimensional stability during ridge preservation.

Methods: 33 patients with a non-molar tooth that required extraction and implant placement were randomly assigned to one of four groups. For group A, the extraction socket was allowed to heal with a blood clot. For group B, the sockets were treated with PRF plug. For Group C, the extraction socket was treated with a mixture of PRF with 0.5cc of Freeze Dried Bone Allograft. Finally, group D sockets received 0.5cc of Freeze Dried Bone Allograft. Clinical measurements of alveolar ridge height and horizontal ridge width were taken after extraction (baseline) as well as at the time of implant placement (3 months).

Results: A statistically significant reduction in the vertical height loss was seen in Group C (PRF+FDBA) 1.5±2.3mm when compared to Group A (blood clot) 4±2.0mm. Similarly, a statistically significant reduction was noted for alveolar vertical height loss for Group B (PRF) 1.6±2.1mm when compared to Group A (blood clot) 4±2.0mm. There was no statistically significant difference in horizontal ridge width between groups.

Conclusion: The results of the study showed that the vertical height loss was significantly less in PRF group (1.6±2.1mm) and PRF with FDBA group (1.5±2.3mm) when compared to blood clot group (4±2.0mm). There was a clear trend for greater ridge width preservation with PRF and FDBA combined.