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Tailor Made Protein Synthesis for HSCs
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https://doi.org/10.1016/j.stem.2014.03.011Abstract
Translation control is a prevalent form of gene expression regulation in developmental and stem cell biology. A recent paper by Signer et al. (2014) measures protein synthesis in the mouse hematopoietic compartment and reveals the importance of diminished protein production for maintaining hematopoietic stem cell function and restraining oncogenic potential.
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