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Lipid -insertion enables targeting functionalization of erythrocyte membrane-cloaked nanoparticles
Published Web Location
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831007/No data is associated with this publication.
Abstract
RBC membrane-cloaked polymeric nanoparticles represent an emerging nanocarrier platform with extended circulation in vivo. A lipid-insertion method is employed to functionalize these nanoparticles without the need for direct chemical conjugation. Insertion of both folate and the nucleolin-targeting aptamer AS1411 shows receptor-specific targeting against model cancer cell lines.
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