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A New Notch for Lung Stem Cells
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https://doi.org/10.1016/j.stem.2015.01.012Abstract
Homeostasis and repair of different lung compartments require the selective activation of specific progenitor/stem cells and their regulated differentiation to yield cell types that fulfill specialized regional functions. In this issue of Cell Stem Cell, Pardo-Saganta et al. (2015) identify Notch signaling as a determinant of basal cell heterogeneity and fate decisions in pseudostratified airways.
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