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A Big Surprise in the Little Zygote: The Curious Business of Losing Methylated Cytosines
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https://doi.org/10.1016/j.stem.2014.09.005Abstract
In stem cell biology, the dynamic addition and removal of 5-methylcytosines (5mCs) are necessary for lineage differentiation, nuclear reprogramming, and embryonic development. Recent investigations have sought to understand the mechanisms of how 5mCs are added and in particular how 5mCs are removed from DNA during embryogenesis.
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