Proceedings of the Vertebrate Pest Conference

Good Laboratory Practice (GLP) guidelines were implemented by the U.S. Environmental Protection Agency in August 1989. The purpose of the standards are to ensure the integrity of laboratory and field studies which are conducted in support of FlFRA permits and pesticide registrations. Since the advent of GLP requirements, the cost of conducting field trials has increased 40 to 200%, depending upon the type of study. The increased expenses associated with laboratory and field testing, coupled with reregistration expenses, and annual EPA and state registration maintenance fees, have placed a tremendous burden on smaller companies in the U.S.