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Endogenous antigen tunes the responsiveness of naive B cells but not T cells
Published Web Location
http://europepmc.org/articles/PMC3438375?pdf=renderNo data is associated with this publication.
Abstract
In humans, up to 75% of newly generated B cells and about 30% of mature B cells show some degree of autoreactivity. Yet, how B cells establish and maintain tolerance in the face of autoantigen exposure during and after development is not certain. Studies o
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