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Kinetics of SARS-CoV-2 Antibody Avidity Maturation and Association with Disease Severity
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https://doi.org/10.1093/cid/ciaa1389Abstract
The kinetics of IgG avidity maturation during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was studied. The IgG avidity assay, using a novel label-free immunoassay technology, revealed a strong correlation between IgG avidity and days since symptom onset. Peak readings were significantly higher in severe than mild disease cases.
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