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Akt-dependent phosphorylation of hepatic Foxo1 is compartmentalized on a WD40/ProF scaffold and is selectively inhibited by aPKC in early phases of diet-induced obesity
Published Web Location
http://europepmc.org/articles/PMC4113067?pdf=renderNo data is associated with this publication.
Abstract
Initiating mechanisms that impair gluconeogenic enzymes and spare lipogenic enzymes in diet-induced obesity (DIO) are obscure. Here, we examined insulin signaling to Akt and atypical protein kinase C (aPKC) in liver and muscle and hepatic enzyme expression
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