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Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologous relationships in mismatch repair-deficient cancer cells

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http://europepmc.org/articles/PMC4189729?pdf=render
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Abstract

© 2014 Tosti et al.; licensee BioMed Central Ltd.Background: The evolutionarily conserved DNA mismatch repair (MMR) system corrects base-substitution and insertion-deletion mutations generated during erroneous replication. The mutation or inactivation of m

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