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Chromatin accessibility reveals insights into androgen receptor activation and transcriptional specificity

Published Web Location

http://europepmc.org/articles/PMC3491416?pdf=render
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Abstract

Background: Epigenetic mechanisms such as chromatin accessibility impact transcription factor binding to DNA and transcriptional specificity. The androgen receptor (AR), a master regulator of the male phenotype and prostate cancer pathogenesis, acts primar

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