Recent ucsflibrary_oafund_pubs items

Reliability of Modified Radiographic Union Score for Tibia Scores in the Evaluation of Femoral Shaft Fractures in a Low-resource Setting

Wed, 15 Jan 2025 00:00:00 +0000

Reliability of Modified Radiographic Union Score for Tibia Scores in the Evaluation of Femoral Shaft Fractures in a Low-resource Setting

An miRNA derived from amelogenin exon4 regulates expression of transcription factor Runx2 by directly targeting upstream activators Nfia and Prkch

Wed, 15 Jan 2025 00:00:00 +0000

An miRNA derived from amelogenin exon4 regulates expression of transcription factor Runx2 by directly targeting upstream activators Nfia and Prkch

A Domain-General Developmental "Do-GooD" Network Model of Prosocial Cognition in Adolescence: A Systematic Review

Wed, 15 Jan 2025 00:00:00 +0000

A Domain-General Developmental "Do-GooD" Network Model of Prosocial Cognition in Adolescence: A Systematic Review

COVID-19 Vaccination and Estimated Public Health Impact in California

Wed, 15 Jan 2025 00:00:00 +0000

COVID-19 Vaccination and Estimated Public Health Impact in California

Longitudinal Trajectories of Memory Performance in Patients with Early-Stage Breast Cancer

Wed, 15 Jan 2025 00:00:00 +0000

Longitudinal Trajectories of Memory Performance in Patients with Early-Stage Breast Cancer

Opportunities to use electronic health record audit logs to improve cancer care

Wed, 15 Jan 2025 00:00:00 +0000

Opportunities to use electronic health record audit logs to improve cancer care

Rapid transition of a preclinical health systems science and social justice course to remote learning in the time of coronavirus

Tue, 16 Jul 2024 00:00:00 +0000

Rapid transition of a preclinical health systems science and social justice course to remote learning in the time of coronavirus

Intracranial temporal bone angiomatoid fibrous histiocytoma: illustrative case

Tue, 16 Jul 2024 00:00:00 +0000

Intracranial temporal bone angiomatoid fibrous histiocytoma: illustrative case

Development of a Consensus-Based Definition of Focused Assessment With Sonography for Trauma in Children

Tue, 3 May 2022 00:00:00 +0000

Development of a Consensus-Based Definition of Focused Assessment With Sonography for Trauma in Children

Tipping the Scales Toward Equity Equilibrium

Tue, 3 May 2022 00:00:00 +0000

A third year medical student shares his approach for translating personal experiences with racial bias into teaching moments that enrich the learning environment.

Responding to the Needs of Persons Living With Dementia and Their Caregivers During the COVID-19 Pandemic: Lessons From the Care Ecosystem

Mon, 25 Apr 2022 00:00:00 +0000

Responding to the Needs of Persons Living With Dementia and Their Caregivers During the COVID-19 Pandemic: Lessons From the Care Ecosystem

Analyzing Precision Medicine Utilization with Real-World Data: A Scoping Review

Mon, 25 Apr 2022 00:00:00 +0000

Analyzing Precision Medicine Utilization with Real-World Data: A Scoping Review

Emergency department antimicrobial use in a low-resource setting: results from a retrospective observational study at a referral hospital in Liberia

Mon, 25 Apr 2022 00:00:00 +0000

Emergency department antimicrobial use in a low-resource setting: results from a retrospective observational study at a referral hospital in Liberia

Primary care gap: factors associated with persistent lack of primary care after hospitalisation

Mon, 25 Apr 2022 00:00:00 +0000

Primary care gap: factors associated with persistent lack of primary care after hospitalisation

Left Ventricle Biomechanics of Low-Flow, Low-Gradient Aortic Stenosis: A Patient-Specific Computational Model

Mon, 25 Apr 2022 00:00:00 +0000

Left Ventricle Biomechanics of Low-Flow, Low-Gradient Aortic Stenosis: A Patient-Specific Computational Model

Transepidermal water loss (TEWL): Environment and pollution-- A systematic review

Mon, 25 Apr 2022 00:00:00 +0000

Transepidermal water loss (TEWL): Environment and pollution-- A systematic review

Calcifying pseudoneoplasm of the neuraxis within the sellar region: illustrative case

Tue, 19 Apr 2022 00:00:00 +0000

Calcifying pseudoneoplasm of the neuraxis within the sellar region: illustrative case

Racial and Socioeconomic Differences in Distance Traveled for Elective Hip Arthroplasty

Wed, 13 Apr 2022 00:00:00 +0000

Racial and Socioeconomic Differences in Distance Traveled for Elective Hip Arthroplasty

Addressing health disparities through implementation science - a need to integrate an equity lens from the outset

Wed, 13 Apr 2022 00:00:00 +0000

Addressing health disparities through implementation science - a need to integrate an equity lens from the outset

Joint Associations of Race, Ethnicity, and Socioeconomic Status With Mortality in the Multiethnic Cohort Study

Wed, 13 Apr 2022 00:00:00 +0000

Joint Associations of Race, Ethnicity, and Socioeconomic Status With Mortality in the Multiethnic Cohort Study

Do private providers give patients what they demand, even if it is inappropriate? A randomised study using unannounced standardised patients in Kenya

Tue, 12 Apr 2022 00:00:00 +0000

Do private providers give patients what they demand, even if it is inappropriate? A randomised study using unannounced standardised patients in Kenya

Risk factor targeting for vaccine prioritization during the COVID-19 pandemic

Tue, 12 Apr 2022 00:00:00 +0000

Risk factor targeting for vaccine prioritization during the COVID-19 pandemic

Abortion Stigma and Its Relationship with Grief, Post-traumatic Stress, and Mental Health-Related Quality of Life After Abortion for Fetal Anomalies

Tue, 12 Apr 2022 00:00:00 +0000

Abortion Stigma and Its Relationship with Grief, Post-traumatic Stress, and Mental Health-Related Quality of Life After Abortion for Fetal Anomalies

Rates of readmission and reoperation following pelvic osteotomy in adolescent patients: a database study evaluating the pediatric health information system

Mon, 11 Apr 2022 00:00:00 +0000

Rates of readmission and reoperation following pelvic osteotomy in adolescent patients: a database study evaluating the pediatric health information system

Fertility preservation in transgender men without discontinuation of testosterone

Mon, 11 Apr 2022 00:00:00 +0000

Fertility preservation in transgender men without discontinuation of testosterone

Hemorrhagic vestibular schwannoma: a case example of vestibular apoplexy syndrome. Illustrative case

Mon, 11 Apr 2022 00:00:00 +0000

Hemorrhagic vestibular schwannoma: a case example of vestibular apoplexy syndrome. Illustrative case

Functional Outcomes and Morbidity in Pediatric Sepsis Survivors: A Tanzanian Experience

Thu, 31 Mar 2022 00:00:00 +0000

Functional Outcomes and Morbidity in Pediatric Sepsis Survivors: A Tanzanian Experience

Optimizing quality of care in patients admitted with chronic obstructive pulmonary disease exacerbation

Thu, 31 Mar 2022 00:00:00 +0000

Optimizing quality of care in patients admitted with chronic obstructive pulmonary disease exacerbation

Use and diagnostic value of liver enzyme tests in the emergency department and subsequent heart failure diagnosis: a retrospective cohort study

Thu, 31 Mar 2022 00:00:00 +0000

Use and diagnostic value of liver enzyme tests in the emergency department and subsequent heart failure diagnosis: a retrospective cohort study

Transient Hyperkalemia Following Treatment of Chronic Hypokalemia: A Case Report and Review of Distal Tubule Physiology

Thu, 31 Mar 2022 00:00:00 +0000

Transient Hyperkalemia Following Treatment of Chronic Hypokalemia: A Case Report and Review of Distal Tubule Physiology

Burst Suppression During General Anesthesia and Postoperative Outcomes: Mini Review

Thu, 31 Mar 2022 00:00:00 +0000

Burst Suppression During General Anesthesia and Postoperative Outcomes: Mini Review

Is positron emission tomography enough to rule out cardiac sarcoidosis? A case report.

Tue, 29 Mar 2022 00:00:00 +0000

Cardiac sarcoidosis (CS) is associated with poor prognosis, yet the clinical diagnosis is often challenging. Advanced cardiac imaging including cardiac magnetic resonance (CMR) and positron emission tomographic (PET) have emerged as useful modalities to diagnose CS.

A 66-year-old woman presented with palpitations. A 24-h Holter monitor detected a high premature ventricular contraction burden of 25.6%. She underwent two transthoracic echocardiograms; both showed normal results. Stress perfusion CMR did not show any evidence of ischaemic aetiology; however, myocardial lesions detected by late gadolinium enhancement (LGE) imaging raised suspicion for CS. While there was no myocardial uptake of fluorodeoxyglucose (FDG) in subsequent cardiac PET, high FDG uptake was seen in hilar lymph nodes. Lymph node biopsy confirmed the diagnosis of sarcoidosis.

Cardiac magnetic resonance and PET imaging are designed to evaluate different aspects CS pathophysiology. The characteristic...

Barriers and Facilitators to Integrating Clinical Breast Examinations With Cervical Cancer Screening Programs in Outpatient Clinics in Western Kenya

Tue, 29 Mar 2022 00:00:00 +0000

Barriers and Facilitators to Integrating Clinical Breast Examinations With Cervical Cancer Screening Programs in Outpatient Clinics in Western Kenya

Superior Long-term Appearance of Strip Craniectomy Compared with Cranial Vault Reconstruction in Metopic Craniosynostosis

Tue, 29 Mar 2022 00:00:00 +0000

Superior Long-term Appearance of Strip Craniectomy Compared with Cranial Vault Reconstruction in Metopic Craniosynostosis

Machine Learning Prediction of Liver Allograft Utilization From Deceased Organ Donors Using the National Donor Management Goals Registry

Wed, 23 Mar 2022 00:00:00 +0000

Early prediction of whether a liver allograft will be utilized for transplantation may allow better resource deployment during donor management and improve organ allocation. The national donor management goals (DMG) registry contains critical care data collected during donor management. We developed a machine learning model to predict transplantation of a liver graft based on data from the DMG registry. METHODS: Several machine learning classifiers were trained to predict transplantation of a liver graft. We utilized 127 variables available in the DMG dataset. We included data from potential deceased organ donors between April 2012 and January 2019. The outcome was defined as liver recovery for transplantation in the operating room. The prediction was made based on data available 12-18 h after the time of authorization for transplantation. The data were randomly separated into training (60%), validation (20%), and test sets (20%). We compared the performance of our models to the...

Emergency general surgery utilization and disparities during COVID-19: an interrupted time-series analysis

Wed, 23 Mar 2022 00:00:00 +0000

OBJECTIVE: We aimed to compare general surgery emergency (GSE) volume, demographics and disease severity before and during COVID-19. BACKGROUND: Presentations to the emergency department (ED) for GSEs fell during the early COVID-19 pandemic. Barriers to accessing care may be heightened, especially for vulnerable populations, and patients delaying care raises public health concerns. METHODS: We included adult patients with ED presentations for potential GSEs at a single quaternary-care hospital from January 2018 to August 2020. To compare GSE volumes in total and by subgroup, an interrupted time-series analysis was performed using the March shelter-in-place order as the start of the COVID-19 period. Bivariate analysis was used to compare demographics and disease severity. RESULTS: 3255 patients (28/week) presented with potential GSEs before COVID-19, while 546 (23/week) presented during COVID-19. When shelter-in-place started, presentations fell by 8.7/week (31%) from the previous...

Compression Therapy for HIV-Associated Kaposi Sarcoma Leg Lymphedema: Results of the Kenyan Improvised Compression for Kaposi Sarcoma Randomized Controlled Trial

Mon, 28 Feb 2022 00:00:00 +0000

Compression Therapy for HIV-Associated Kaposi Sarcoma Leg Lymphedema: Results of the Kenyan Improvised Compression for Kaposi Sarcoma Randomized Controlled Trial

Self-reported provision of person-centred maternity care among providers in Kenya and Ghana: scale validation and examination of associated factors

Fri, 25 Feb 2022 00:00:00 +0000

Self-reported provision of person-centred maternity care among providers in Kenya and Ghana: scale validation and examination of associated factors

Turmeric-Induced Hepatotoxicity: Report of 2 Cases

Fri, 25 Feb 2022 00:00:00 +0000

Turmeric-Induced Hepatotoxicity: Report of 2 Cases

Odds of return: a prospective study using provider assessment to predict short-term patient return visits to the emergency department

Thu, 24 Feb 2022 00:00:00 +0000

Odds of return: a prospective study using provider assessment to predict short-term patient return visits to the emergency department

Mycobacterium Avium Complex Infection as a Rare Cause of Cerebral Mass Lesion and IRIS in a Patient with AIDS: Case Report and Review of the Literature

Thu, 24 Feb 2022 00:00:00 +0000

Mycobacterium Avium Complex Infection as a Rare Cause of Cerebral Mass Lesion and IRIS in a Patient with AIDS: Case Report and Review of the Literature

Risk Factors Associated With Early-Onset Esophageal Cancer in Tanzania

Tue, 22 Feb 2022 00:00:00 +0000

Risk Factors Associated With Early-Onset Esophageal Cancer in Tanzania

Understanding quality of contraceptive services from women’s perspectives in Gujarat, India: a focus group study

Fri, 18 Feb 2022 00:00:00 +0000

OBJECTIVES: Understanding quality of contraceptive care from clients' perspectives is critical to ensuring acceptable and non-harmful services, yet little qualitative research has been dedicated to this topic. India's history of using incentives to promote contraceptive use, combined with reports of unsafe conditions in sterilisation camps, make a focus on quality important. The study objective was to understand women's experiences with and preferences for contraceptive counselling and care in the public sector in India. DESIGN: Qualitative study using eight focus group discussions (FGDs). FGDs were thematically analysed using a framework approach. SETTING: Rural and urban areas in one district in Gujarat. PARTICIPANTS: 31 sterilisation and 42 reversible contraceptive users who were married and represented different backgrounds. Inclusion criteria were: (1) female, (2) at least 18 years and (3) receipt of contraception services in the last 6 months from public health services. RESULTS:...

Study protocol: a pilot randomised waitlist-controlled trial of a dyadic mobile health intervention for black sexual-minority male couples with HIV in the USA

Mon, 15 Nov 2021 00:00:00 +0000

HIV care engagement is lower among black sexual-minority men relative to other racial/ethnic groups of sexual-minority men. Being in a primary relationship is generally associated with more successful HIV care engagement across various populations. However, among black sexual-minority men, the association between primary relationship status and HIV-related outcomes is inconsistent across the HIV care continuum. Given the ubiquity of mobile technology access and use among racial/ethnic minority communities, leveraging mobile technology for HIV care engagement appears a promising intervention strategy. This paper outlines the protocol of the LetSync study, a pilot randomised controlled trial of a mobile health app intervention developed using the Framework of Dyadic HIV Care Engagement to improve care-engagement outcomes among black sexual-minority male couples living with HIV.

Eighty black sexual-minority men in couples (n=160) will be enrolled to pilot test the LetSync...

Diagnostic accuracy of a liquid chromatography-tandem mass spectrometry assay in small hair samples for rifampin-resistant tuberculosis drug concentrations in a routine care setting

Mon, 15 Nov 2021 00:00:00 +0000

BackgroundTreatment monitoring of drug-resistant tuberculosis (DR-TB) in resource-limited settings is challenging. We developed a multi-analyte assay for eleven anti-TB drugs in small hair samples as an objective metric of drug exposure.MethodsSmall hair samples were collected from participants at various timepoints during directly observed RR-TB treatment at an inpatient tertiary referral facility in South Africa (DR-TB cohort). We assessed qualitative determination (i.e., detection above limit of detection) of bedaquiline, linezolid, clofazimine, pretomanid, levofloxacin, moxifloxacin, pyrazinamide, isoniazid, ethambutol, ethionamide, and prothionamide in an LC-MS/MS index panel assay against a reference standard of inpatient treatment records. Because treatment regimens prior to hospitalization were not available, we also analyzed specificity (for all drugs except isoniazid) using an external cohort of HIV-positive patients treated for latent TB infection with daily isoniazid...

The Role of Liver Imaging in Hereditary Hemorrhagic Telangiectasia

Mon, 15 Nov 2021 00:00:00 +0000

The Role of Liver Imaging in Hereditary Hemorrhagic Telangiectasia

Racial and Gender Shoulder Arthroplasty Utilization Disparities of High- and Low-Volume Centers in New York State

Tue, 19 Oct 2021 00:00:00 +0000

Racial and Gender Shoulder Arthroplasty Utilization Disparities of High- and Low-Volume Centers in New York State

Neurosarcoidosis: Pathophysiology, Diagnosis, and Treatment

Tue, 19 Oct 2021 00:00:00 +0000

Neurosarcoidosis: Pathophysiology, Diagnosis, and Treatment

Relationship between food insecurity and smoking status among women living with and at risk for HIV in the USA: a cohort study

Wed, 15 Sep 2021 00:00:00 +0000

Relationship between food insecurity and smoking status among women living with and at risk for HIV in the USA: a cohort study

California's COVID-19 Virtual Training Academy: Rapid Scale-Up of a Statewide Contact Tracing and Case Investigation Workforce Training Program

Wed, 15 Sep 2021 00:00:00 +0000

California's COVID-19 Virtual Training Academy: Rapid Scale-Up of a Statewide Contact Tracing and Case Investigation Workforce Training Program

Perspectives on Spain's legislative experience providing access to healthcare to irregular migrants: a qualitative interview study

Wed, 15 Sep 2021 00:00:00 +0000

Perspectives on Spain's legislative experience providing access to healthcare to irregular migrants: a qualitative interview study

Intramedullary nailing versus external fixation for open tibia fractures in Tanzania: a cost analysis

Wed, 15 Sep 2021 00:00:00 +0000

Intramedullary nailing versus external fixation for open tibia fractures in Tanzania: a cost analysis

Rates of Serious Surgical Errors in California and Plans to Prevent Recurrence

Wed, 8 Sep 2021 00:00:00 +0000

Rates of Serious Surgical Errors in California and Plans to Prevent Recurrence

Mobile health strategies for blood pressure self-management in urban populations with digital barriers: systematic review and meta-analyses

Tue, 7 Sep 2021 00:00:00 +0000

Mobile health (mHealth) technologies improve hypertension outcomes, but it is unknown if this benefit applies to all populations. This review aimed to describe the impact of mHealth interventions on blood pressure outcomes in populations with disparities in digital health use. We conducted a systematic search to identify studies with systolic blood pressure (SBP) outcomes located in urban settings in high-income countries that included a digital health disparity population, defined as mean age ≥65 years; lower educational attainment (≥60% ≤high school education); and/or racial/ethnic minority (<50% non-Hispanic White for US studies). Interventions were categorized using an established self-management taxonomy. We conducted a narrative synthesis; among randomized clinical trials (RCTs) with a six-month SBP outcome, we conducted random-effects meta-analyses. Twenty-nine articles (representing 25 studies) were included, of which 15 were RCTs. Fifteen studies used text messaging;...

Increasing the use of multimodal analgesia during adult surgery in a tertiary academic anaesthesia department

Tue, 7 Sep 2021 00:00:00 +0000

OBJECTIVE: Multimodal analgesia pathways have been shown to reduce opioid use and side effects in surgical patients. A quality improvement initiative was implemented to increase the use of multimodal analgesia in adult patients presenting for general anaesthesia at an academic tertiary care centre. The aim of this study was to increase adoption of a perioperative multimodal analgesia protocol across a broad population of surgical patients. The use of multimodal analgesia was tracked as a process metric. Our primary outcome was opioid use normalised to oral morphine equivalents (OME) intraoperatively, in the postanaesthesia care unit (PACU), and 48 hours postoperatively. Pain scores and use of antiemetics were measured as balancing metrics. METHODS: We conducted a quality improvement study of a multimodal analgesia protocol implemented for adult (≥18 and≤70) non-transplant patients undergoing general anaesthesia (≥180 min). Components of multimodal analgesia were defined as (1)...

Evaluation of Dual-port versus Single-port Tissue Expanders in Postmastectomy Breast Reconstruction

Wed, 1 Sep 2021 00:00:00 +0000

Evaluation of Dual-port versus Single-port Tissue Expanders in Postmastectomy Breast Reconstruction

Role of mTORC2 in biphasic regulation of brown fat metabolism in response to mild and severe cold

Wed, 1 Sep 2021 00:00:00 +0000

Role of mTORC2 in biphasic regulation of brown fat metabolism in response to mild and severe cold

WYZ: a pilot study protocol for designing and developing a mobile health application for engagement in HIV care and medication adherence in youth and young adults living with HIV

Wed, 1 Sep 2021 00:00:00 +0000

WYZ: a pilot study protocol for designing and developing a mobile health application for engagement in HIV care and medication adherence in youth and young adults living with HIV

Fixation of intertrochanteric femur fractures using the SIGN intramedullary nail augmented by a lateral plate in a resource-limited setting without intraoperative fluoroscopy: assessment of functional outcomes at one-year follow-up at Juba Teaching Hospital

Fri, 13 Aug 2021 00:00:00 +0000

Fixation of intertrochanteric femur fractures using the SIGN intramedullary nail augmented by a lateral plate in a resource-limited setting without intraoperative fluoroscopy: assessment of functional outcomes at one-year follow-up at Juba Teaching Hospital

Intensive Home Blood Pressure Lowering in Advanced Chronic Kidney Disease: A Pilot Randomized Controlled Trial Protocol

Tue, 10 Aug 2021 00:00:00 +0000

Intensive Home Blood Pressure Lowering in Advanced Chronic Kidney Disease: A Pilot Randomized Controlled Trial Protocol

Barriers and Facilitators to Accessing Health Services for People Without Documentation Status in an Anti-Immigrant Era: A Socioecological Model

Tue, 10 Aug 2021 00:00:00 +0000

Barriers and Facilitators to Accessing Health Services for People Without Documentation Status in an Anti-Immigrant Era: A Socioecological Model

Smoking Cessation Pharmacotherapy Utilization and Costs to a Medicaid Managed Care Plan

Tue, 10 Aug 2021 00:00:00 +0000

Smoking Cessation Pharmacotherapy Utilization and Costs to a Medicaid Managed Care Plan

Social and Behavioral Correlates of Sexually Transmitted Infections among Men who Have Sex with Men who Use Alcohol in the San Francisco Bay Area

Tue, 10 Aug 2021 00:00:00 +0000

Social and Behavioral Correlates of Sexually Transmitted Infections among Men who Have Sex with Men who Use Alcohol in the San Francisco Bay Area

Assessment of clinical and radiographic outcomes following retrograde versus antegrade nailing of infraisthmic femoral shaft fractures without the use of intraoperative fluoroscopy in Tanzania

Tue, 10 Aug 2021 00:00:00 +0000

Assessment of clinical and radiographic outcomes following retrograde versus antegrade nailing of infraisthmic femoral shaft fractures without the use of intraoperative fluoroscopy in Tanzania

Macrophages and Their Organ Locations Shape Each Other in Development and Homeostasis - A Drosophila Perspective

Mon, 9 Aug 2021 00:00:00 +0000

Macrophages and Their Organ Locations Shape Each Other in Development and Homeostasis - A Drosophila Perspective

A Prospective Study of Patient-Reported Xerostomia-Related Outcome After Parotidectomy

Mon, 9 Aug 2021 00:00:00 +0000

A Prospective Study of Patient-Reported Xerostomia-Related Outcome After Parotidectomy

Citywide serosurveillance of the initial SARS-CoV-2 outbreak in San Francisco using electronic health records

Mon, 9 Aug 2021 00:00:00 +0000

Serosurveillance provides a unique opportunity to quantify the proportion of the population that has been exposed to pathogens. Here, we developed and piloted Serosurveillance for Continuous, ActionabLe Epidemiologic Intelligence of Transmission (SCALE-IT), a platform through which we systematically tested remnant samples from routine blood draws in two major hospital networks in San Francisco for SARS-CoV-2 antibodies during the early months of the pandemic. Importantly, SCALE-IT allows for algorithmic sample selection and rich data on covariates by leveraging electronic health record data. We estimated overall seroprevalence at 4.2%, corresponding to a case ascertainment rate of only 4.9%, and identified important heterogeneities by neighborhood, homelessness status, and race/ethnicity. Neighborhood seroprevalence estimates from SCALE-IT were comparable to local community-based surveys, while providing results encompassing the entire city that have been previously unavailable....

Characterizing online crowdfunding campaigns for patients with kidney cancer

Mon, 9 Aug 2021 00:00:00 +0000

Characterizing online crowdfunding campaigns for patients with kidney cancer

HLA Alleles B53:01 and C06:02 Are Associated With Higher Risk of P. falciparum Parasitemia in a Cohort in Uganda

Mon, 9 Aug 2021 00:00:00 +0000

HLA Alleles B*53:01 and C*06:02 Are Associated With Higher Risk of P. falciparum Parasitemia in a Cohort in Uganda

A Baffling Bump: A Case Report of an Unusual Chest Wall Mass in a Pediatric Patient

Tue, 27 Jul 2021 00:00:00 +0000

Introduction: Chest wall masses are rare in children, but the differential diagnosis is broad and can include traumatic injury, neoplasm, and inflammatory or infectious causes. We report a novel case of an eight-year-old, previously healthy female who presented to the emergency department (ED) with one month of cough, fevers, weight loss, and an anterior chest wall mass.

Case Report: The patient’s ultimate diagnosis was necrotizing pneumonia with pneumatocele extending into the chest wall. This case is notable for the severity of the patient’s pulmonary disease given its extension through the chest wall, and for the unique speciation of her infection.

Conclusion: Although necrotizing pneumonia is a rare complication of community-acquired pneumonia, it is important for the emergency physician to recognize it promptly as it indicates severe progression of pulmonary disease even in children with normal and stable vital...

Refractory pemphigus vulgaris successfully treated with ofatumumab

Mon, 19 Jul 2021 00:00:00 +0000

Refractory pemphigus vulgaris successfully treated with ofatumumab

Landscape analysis for a community-designed intervention to enhance early childhood development in San Francisco

Mon, 19 Jul 2021 00:00:00 +0000

Landscape analysis for a community-designed intervention to enhance early childhood development in San Francisco

Evaluating the Impact of a School-Based Youth-Led Health Education Program for Adolescent Females in Mumbai, India

Mon, 19 Jul 2021 00:00:00 +0000

Evaluating the Impact of a School-Based Youth-Led Health Education Program for Adolescent Females in Mumbai, India

COVID-19 Impact on Community-Based Participatory Randomized Controlled Trials--Lessons From the Oral Health Disparities in Children Consortium

Fri, 9 Jul 2021 00:00:00 +0000

COVID-19 Impact on Community-Based Participatory Randomized Controlled Trials--Lessons From the Oral Health Disparities in Children Consortium

Conducting Internet-Based Visits for Onboarding Populations With Limited Digital Literacy to an mHealth Intervention: Development of a Patient-Centered Approach

Thu, 8 Jul 2021 00:00:00 +0000

BACKGROUND: The COVID-19 pandemic has propelled patient-facing research to shift to digital and telehealth strategies. If these strategies are not adapted for minority patients of lower socioeconomic status, health inequality will further increase. Patient-centered models of care can successfully improve access and experience for minority patients. OBJECTIVE: This study aims to present the development process and preliminary acceptability of altering in-person onboarding procedures into internet-based, remote procedures for a mobile health (mHealth) intervention in a population with limited digital literacy. METHODS: We actively recruited safety-net patients (English- and Spanish-speaking adults with diabetes and depression who were receiving care at a public health care delivery system in San Francisco, United States) into a randomized controlled trial of text messaging support for physical activity. Because of the COVID-19 pandemic, we modified the in-person recruitment and...

An abdominal skin lesion: to lump or split? a case presentation

Thu, 8 Jul 2021 00:00:00 +0000

Syphilis has many atypical morphologies which can present a diagnostic challenge, especially in patients with HIV/AIDS who may have multiple concurrent conditions. We describe a 41-year-old man with recently diagnosed HIV who was admitted for acute right vision loss and a diffuse rash with involvement of the palms and soles. He received diagnoses of secondary syphilis and Kaposi sarcoma in the setting of AIDS. Examination revealed an unusual dark brown-to-purple umbilicated papule with a necrotic center on the abdomen, raising a diagnostic dilemma. Skin biopsy showed secondary syphilis, despite the concurrent diagnosis of Kaposi sarcoma. The patient was treated with antibiotic and antiretroviral therapy and symptoms resolved. This case aims to share the clinical reasoning behind diagnosing a patient with HIV/AIDS with multiple concurrent conditions and to raise awareness of the many atypical cutaneous manifestations of secondary syphilis.

Healthcare Utilization of Complex Chronically Ill Children Managed by a Telehealth-Based Team

Wed, 7 Jul 2021 00:00:00 +0000

Healthcare Utilization of Complex Chronically Ill Children Managed by a Telehealth-Based Team

Association of Travel Distance to Nearest Abortion Facility With Rates of Abortion

Wed, 7 Jul 2021 00:00:00 +0000

Association of Travel Distance to Nearest Abortion Facility With Rates of Abortion

Research Equity in Otolaryngology-Head and Neck Surgery

Wed, 7 Jul 2021 00:00:00 +0000

Research Equity in Otolaryngology-Head and Neck Surgery

Development of the Mobile Technology Vulnerability Scale among Youth and Young Adults Living with HIV

Tue, 6 Jul 2021 00:00:00 +0000

Development of the Mobile Technology Vulnerability Scale among Youth and Young Adults Living with HIV

Missed Opportunities for HIV Prevention in Perinatal Care Settings in the United States

Fri, 2 Jul 2021 00:00:00 +0000

Missed Opportunities for HIV Prevention in Perinatal Care Settings in the United States

Lacosamide induced Brugada I morphology in the setting of septicemia

Wed, 30 Jun 2021 00:00:00 +0000

Lacosamide induced Brugada I morphology in the setting of septicemia

Addressing HIV care, mental health and substance use among youth and young adults in the Bay Area: description of an intervention to improve information, motivation and behavioural skills

Wed, 30 Jun 2021 00:00:00 +0000

Addressing HIV care, mental health and substance use among youth and young adults in the Bay Area: description of an intervention to improve information, motivation and behavioural skills

Disseminated-cutaneous sporotrichosis in an immunocompetent adult

Wed, 30 Jun 2021 00:00:00 +0000

Disseminated-cutaneous sporotrichosis in an immunocompetent adult

The impact of stopping and starting indoor residual spraying on malaria burden in Uganda

Wed, 30 Jun 2021 00:00:00 +0000

The impact of stopping and starting indoor residual spraying on malaria burden in Uganda

Trends in Home Birth Information Seeking in the United States and United Kingdom During the COVID-19 Pandemic

Wed, 30 Jun 2021 00:00:00 +0000

Trends in Home Birth Information Seeking in the United States and United Kingdom During the COVID-19 Pandemic

Driving distances and loss to follow-up after hematopoietic cell transplantation

Wed, 12 May 2021 00:00:00 +0000

Driving distances and loss to follow-up after hematopoietic cell transplantation

Patient and Caregiver Experience with Outpatient Palliative Care Telemedicine Visits

Wed, 12 May 2021 00:00:00 +0000

Patient and Caregiver Experience with Outpatient Palliative Care Telemedicine Visits

Evidence of state-dependence in the effectiveness of responsive neurostimulation for seizure modulation

Thu, 6 May 2021 00:00:00 +0000

Evidence of state-dependence in the effectiveness of responsive neurostimulation for seizure modulation

Couples-focused intervention to improve engagement in HIV care: protocol for a randomised controlled trial

Tue, 4 May 2021 00:00:00 +0000

INTRODUCTION: Advances in HIV treatment have proven to be effective in increasing virological suppression, thereby decreasing morbidity, and increasing survival. Medication adherence is an important factor in reducing viral load among people living with HIV (PLWH) and in the elimination of transmission of HIV to uninfected partners. Achieving optimal medication adherence involves individuals taking their medications every day or as prescribed by their provider. However, not all PLWH in the USA are engaged in care, and only a minority have achieved suppressed viral load (viral load that is lower than the detectable limit of the assay). Sexual and gender minorities (SGM; those who do not identify as heterosexual or those who do not identify as the sex they were assigned at birth) represent a high-risk population for poor clinical outcomes and increased risk of HIV transmission, as they face barriers that can prevent optimal engagement in HIV care. Research in dyadic support, specifically...

Botulinum toxin for chronic parotid sialadenitis: A case series and systematic review

Tue, 4 May 2021 00:00:00 +0000

Botulinum toxin for chronic parotid sialadenitis: A case series and systematic review

Early Recurrent Carpal Tunnel Syndrome in Patients with Mucopolysaccharidoses

Fri, 23 Apr 2021 00:00:00 +0000

Supplemental Digital Content is available in the text.Summary:Early-onset carpal tunnel syndrome (CTS) is a well-known manifestation of mucopolysaccharidoses (MPS) due to excessive deposition of glycosaminoglycans in soft tissues. Standard treatment has been carpal tunnel release surgery, with the conventional technique of dividing the transverse carpal ligament. With advancement of treatments for MPS, these patients now have a longer life expectancy and are presenting with recurrent CTS. Management of recurrent CTS in these patients is not well studied. Here, we report 2 cases of recurrent CTS in MPS patients after a carpal tunnel release operation. We describe the findings on repeat operations and propose a unique technique for treating CTS in MPS patients to minimize recurrence during the initial CTS surgery. Our method involves resection of a portion of the transverse carpal ligament and use of a hypothenar fat pad flap over the median nerve.

Early Recurrent Carpal Tunnel Syndrome in Patients with Mucopolysaccharidoses

Wed, 21 Apr 2021 00:00:00 +0000

Early Recurrent Carpal Tunnel Syndrome in Patients with Mucopolysaccharidoses

Evidence of state-dependence in the effectiveness of responsive neurostimulation for seizure modulation

Wed, 21 Apr 2021 00:00:00 +0000

Evidence of state-dependence in the effectiveness of responsive neurostimulation for seizure modulation

Single-cell transcriptional profiling of human thymic stroma uncovers novel cellular heterogeneity in the thymic medulla.

Tue, 20 Apr 2021 00:00:00 +0000

The thymus' key function in the immune system is to provide the necessary environment for the development of diverse and self-tolerant T lymphocytes. While recent evidence suggests that the thymic stroma is comprised of more functionally distinct subpopulations than previously appreciated, the extent of this cellular heterogeneity in the human thymus is not well understood. Here we use single-cell RNA sequencing to comprehensively profile the human thymic stroma across multiple stages of life. Mesenchyme, pericytes and endothelial cells are identified as potential key regulators of thymic epithelial cell differentiation and thymocyte migration. In-depth analyses of epithelial cells reveal the presence of ionocytes as a medullary population, while the expression of tissue-specific antigens is mapped to different subsets of epithelial cells. This work thus provides important insight on how the diversity of thymic cells is established, and how this heterogeneity contributes...

Acute esophageal necrosis complicated by refractory stricture formation

Tue, 20 Apr 2021 00:00:00 +0000

Acute esophageal necrosis complicated by refractory stricture formation

Measuring Satisfaction and Comfort with Gender Identity and Gender Expression among Transgender Women: Development and Validation of the Psychological Gender Affirmation Scale

Sat, 17 Apr 2021 00:00:00 +0000

Measuring Satisfaction and Comfort with Gender Identity and Gender Expression among Transgender Women: Development and Validation of the Psychological Gender Affirmation Scale

Single-cell transcriptional profiling of human thymic stroma uncovers novel cellular heterogeneity in the thymic medulla

Tue, 13 Apr 2021 00:00:00 +0000

Single-cell transcriptional profiling of human thymic stroma uncovers novel cellular heterogeneity in the thymic medulla

"What if They Are Pre-conception? What Should We Do?": Knowledge, Practices, and Preferences for Safer Conception Among Women Living With HIV and Healthcare Providers in Gaborone, Botswana

Tue, 13 Apr 2021 00:00:00 +0000

"What if They Are Pre-conception? What Should We Do?": Knowledge, Practices, and Preferences for Safer Conception Among Women Living With HIV and Healthcare Providers in Gaborone, Botswana

Reducing the global burden of Preterm Birth through knowledge transfer and exchange: a research agenda for engaging effectively with policymakers

Fri, 9 Apr 2021 00:00:00 +0000

Reducing the global burden of Preterm Birth through knowledge transfer and exchange: a research agenda for engaging effectively with policymakers