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    <title>Recent ucsdsom_isp items</title>
    <link>https://escholarship.org/uc/ucsdsom_isp/rss</link>
    <description>Recent eScholarship items from Independent Study Projects</description>
    <pubDate>Fri, 15 May 2026 04:37:57 +0000</pubDate>
    <item>
      <title>Adolescent metabolic syndrome risk is increased with higher infancy weight gain and decreased with longer breast feeding</title>
      <link>https://escholarship.org/uc/item/9z46q0xq</link>
      <description>Adolescent metabolic syndrome risk is increased with higher infancy weight gain and decreased with longer breast feeding</description>
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      <pubDate>Thu, 17 Nov 2022 00:00:00 +0000</pubDate>
      <author>
        <name>Khuc, Kim</name>
      </author>
    </item>
    <item>
      <title>Spot urine sodium measurements do not accurately estimate dietary sodium intake in chronic kidney disease.</title>
      <link>https://escholarship.org/uc/item/6bs477v7</link>
      <description>&lt;p&gt;Sodium intake influences blood pressure and proteinuria, yet the impact on long-term outcomes is uncertain in chronic kidney disease (CKD). Accurate assessment is essential for clinical and public policy recommendations, but few large-scale studies use 24-h urine collections. Recent studies that used spot urine sodium and associated estimating equations suggest that they may provide a suitable alternative, but their accuracy in patients with CKD is unknown.&lt;/p&gt;&lt;p&gt;We compared the accuracy of 4 equations [the Nerbass, INTERSALT (International Cooperative Study on Salt, Other Factors, and Blood Pressure), Tanaka, and Kawasaki equations] that use spot urine sodium to estimate 24-h sodium excretion in patients with moderate to advanced CKD.&lt;/p&gt;&lt;p&gt;We evaluated the accuracy of spot urine sodium to predict mean 24-h urine sodium excretion over 9 mo in 129 participants with stage 3-4 CKD. Spot morning urine sodium was used in 4 estimating equations. Bias, precision, and accuracy were...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/6bs477v7</guid>
      <pubDate>Thu, 17 Nov 2022 00:00:00 +0000</pubDate>
      <author>
        <name>Dougher, Carly E</name>
      </author>
      <author>
        <name>Rifkin, Dena E</name>
      </author>
      <author>
        <name>Anderson, Cheryl Am</name>
      </author>
      <author>
        <name>Smits, Gerard</name>
      </author>
      <author>
        <name>Persky, Martha S</name>
      </author>
      <author>
        <name>Block, Geoffrey A</name>
      </author>
      <author>
        <name>Ix, Joachim H</name>
      </author>
    </item>
    <item>
      <title>Coronary Artery Aneurysms in Kawasaki Disease: Risk Factors for Progressive Disease and Adverse Cardiac Events in the US Population</title>
      <link>https://escholarship.org/uc/item/5k65j8nw</link>
      <description>Background&lt;p&gt;The natural history of coronary artery aneurysms (CAA) after intravenous immunoglobulin (IVIG) treatment in the United States is not well described. We describe the natural history of CAA in US Kawasaki disease (KD) patients and identify factors associated with major adverse cardiac events (MACE) and CAA regression.&lt;/p&gt;Methods and Results&lt;p&gt;We evaluated all KD patients with CAA at 2 centers from 1979 to 2014. Factors associated with CAA regression, maximum CA z‐score over time (zMax), and MACE were analyzed. We performed a matched analysis of treatment effect on likelihood of CAA regression. Of 2860 KD patients, 500 (17%) had CAA, including 90 with CAA z‐score &amp;gt;10. Most (91%) received IVIG within 10&amp;nbsp;days of illness, 32% received &amp;gt;1 IVIG, and 27% received adjunctive anti‐inflammatory medications. CAA regression occurred in 75%. Lack of CAA regression and higher CAA zMax were associated with earlier era, larger CAA z‐score at diagnosis, and bilateral CAA...</description>
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      <pubDate>Thu, 17 Nov 2022 00:00:00 +0000</pubDate>
      <author>
        <name>Friedman, Kevin G.</name>
      </author>
      <author>
        <name>Gauvreau, Kimberly</name>
      </author>
      <author>
        <name>Hamaoka‐Okamoto, Akiko</name>
      </author>
      <author>
        <name>Tang, Alexander</name>
      </author>
      <author>
        <name>Berry, Erika</name>
      </author>
      <author>
        <name>Tremoulet, Adriana H.</name>
      </author>
      <author>
        <name>Mahavadi, Vidya S.</name>
      </author>
      <author>
        <name>Baker, Annette</name>
      </author>
      <author>
        <name>deFerranti, Sarah D.</name>
      </author>
      <author>
        <name>Fulton, David R.</name>
      </author>
      <author>
        <name>Burns, Jane C.</name>
      </author>
      <author>
        <name>Newburger, Jane W.</name>
      </author>
    </item>
    <item>
      <title>Parental and Youth Understanding of the Informed Consent Process for Pediatric Endoscopy</title>
      <link>https://escholarship.org/uc/item/3369f5wd</link>
      <description>Parental and Youth Understanding of the Informed Consent Process for Pediatric Endoscopy</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/3369f5wd</guid>
      <pubDate>Thu, 17 Nov 2022 00:00:00 +0000</pubDate>
      <author>
        <name>Jubbal, Kevin</name>
      </author>
      <author>
        <name>Chun, Stanford</name>
      </author>
      <author>
        <name>Chang, Jeremy</name>
      </author>
      <author>
        <name>Zhang, Sherry</name>
      </author>
      <author>
        <name>Terrones, Laura</name>
      </author>
      <author>
        <name>Huang, Jeannie S</name>
      </author>
    </item>
    <item>
      <title>Focused clinical multi-disciplinary ISP final project: substance use disorder and PTSD</title>
      <link>https://escholarship.org/uc/item/9g45j6zv</link>
      <description>Multiple theories about the association between Post Traumatic Stress Disorder (PTSD) and Substance Use Disorder (SUD) have been proposed, but there is yet to be a common consensus on their exact relationship. Regardless of the etiology of their association, it is reasonable to suggest that the interaction between SUD and comorbid PTSD is complex. The intention of this project was not to dive deeper into the suggested theoretical models, but rather to focus on understanding how these conditions affect patients and on a pragmatic approach to treatment. This was based largely in principle on two observations from prior studies. One of which was the fact that patients with the SUD/PTSD are more likley to struggle with treatment for substance use disorder in regards to retention and periods of abstinence. Second was the realization that patients with comorbid disease have higher rates of homelessness, physical health problems, psychiatric cormorbities, and psychosocial impairment...</description>
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      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Cardillo, Nicholas</name>
      </author>
    </item>
    <item>
      <title>Growth chart basics in 3 minutes: A resource for improving parent’s understanding of growth charts</title>
      <link>https://escholarship.org/uc/item/96k0j59w</link>
      <description>As information technology continues to improve, patients are given access to increasing amounts of their health data. Health applications such as Epic MyChart provide an easily accessible archive of information for both patients and, in the case of pediatrics, parents. With increasing amounts of available information there is a concurrent need to provide education about interpretation. This study aimed to create a short, parent-focused, educational video to convey high-yield information regarding growth chart data. A pre- and post-survey were administered in conjunction with the educational video using QR codes at pediatric offices in La Jolla. We found, in general, parents felt well-equipped to be active participants in their child’s health, but identified some areas for improvement regarding perceptions of health.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/96k0j59w</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Kroesing Albino, Nicholas</name>
      </author>
    </item>
    <item>
      <title>Massage therapy in the neurologic intensive care unit</title>
      <link>https://escholarship.org/uc/item/90k2v26j</link>
      <description>Massage therapy in the NICU appears to be safe, feasible, and improves patient pain self-assessment without vital sign instability.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/90k2v26j</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Chang, Victoria A.</name>
      </author>
      <author>
        <name>Raskin, Erin</name>
      </author>
      <author>
        <name>Karanjia, Navaz</name>
      </author>
      <author>
        <name>LaBuzetta, Jamie N.</name>
      </author>
    </item>
    <item>
      <title>Reducing opioid doses prescribed from a pediatric emergency department</title>
      <link>https://escholarship.org/uc/item/8w98x2fk</link>
      <description>Background: opioid overdose and abuse have reaches epidemic rates in the United States. Legitimate prescriptions are a large source of opioid misuse in adults and adolescents. The goal of this quality improvement project was to reduce opioid exposure from our pediatric emergency department (ED).</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/8w98x2fk</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>DeMartinis, Nicole C.</name>
      </author>
      <author>
        <name>Shah, Seema</name>
      </author>
      <author>
        <name>Etkin, Mark L.</name>
      </author>
      <author>
        <name>Kuelbs, Cynthia L.</name>
      </author>
      <author>
        <name>Huang, Jeannie S.</name>
      </author>
      <author>
        <name>Bryl, Amy W.</name>
      </author>
    </item>
    <item>
      <title>Implementing bilingual labor &amp;amp; delivery education modules for the centering pregnancy  curriculum at Chula Vista Medical Plaza</title>
      <link>https://escholarship.org/uc/item/7h75f9z3</link>
      <description>The aim of this project was to create supplemental education modules to assist in the labor and delivery sessions, Sessions 5 and 6, of the CenteringPregnancy curriculum hosted at Chula Vista Medical Plaza in order to allow participants that are monolingual in Spanish to better understand the processes of labor and delivery. The activities already in place from the curriculum made assumptions about patient understandings of their own anatomy, what uterine contractions are, and stages of labor. By designing education tools that were more visual, barriers in language that prevent understanding of educational content could be overcome. Most importantly, participants could feel empowered in their pregnancies by understanding the physiological changes their bodies would experience during labor and delivery.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/7h75f9z3</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Watler, Sarah Isabella Watler</name>
      </author>
    </item>
    <item>
      <title>Patient attitudes regarding online sources of health information</title>
      <link>https://escholarship.org/uc/item/75b562ng</link>
      <description>Health literacy, generally defined as an individual's skill in obtaining and understanding information related to their health, has been shown to have significant impact on patient outcomes. Low health literacy is associated with higher rates of hospitalization and health care resource utilization, higher prevalence and severity of chronic disease, and worsened global measures of health including mortality. Poor health literacy is prevalent in the United States; as many as 36 percent of the population demonstrates limited health literacy. Rates are higher in certain subgroups such as the elderly, minorities, and those of low education or socioeconomic status. Given the wide prevalence and far-ranging effects on long-term health outcomes, efforts to improve health literacy nationally clearly offer significant benefits across the population. This study surveyed ambulatory patients at four clinic sites within the UCSD health care system. Patients were offered participation in the...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/75b562ng</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Heimler, Graham</name>
      </author>
      <author>
        <name>Slater, Daniel</name>
      </author>
      <author>
        <name>Shahtaji, Alan</name>
      </author>
      <author>
        <name>Lynch, Allison</name>
      </author>
    </item>
    <item>
      <title>Development of an organotypic slice culture protocol and proof of cultured sample viability</title>
      <link>https://escholarship.org/uc/item/6t1143m4</link>
      <description>Ischemia reperfusion injury is a major cause of morbidity and mortality worldwide. A better understanding of the cardioprotective effects of anesthetics is needed to open up opportunities for research in a variety of medical fields such as internal medicine, geriatrics, cardiology, surgery and anesthesiology. Furthermore, a better understanding of the mechanism of pre- and post- conditioning of anesthetics may lead to the development of novel cardioprotective therapeutics for older patients who are in need of cardiac surgery. This project takes a novel approach towards the study of cardiac tissue in vivo. Previously, human samples were obtained from patient surgeries. This approach presented the scientific community with several problems. First, the samples were scarce and difficult to obtain. Second, the experiments and the time available was very limited due to the viability of the tissue. New approaches include the culturing of cardiac myocytes. However, the lack of the microenvironment...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/6t1143m4</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Lyubasyuk, Aleksandr</name>
      </author>
    </item>
    <item>
      <title>Food insecurity and food pantry utilization at the UCSD Student-Run Free Clinics</title>
      <link>https://escholarship.org/uc/item/6px693t8</link>
      <description>In a recent study, 74% of 430 UCSD Student-Run Free Clinic (UCSDSRFC) patients were food insecure using the 6-item USDA food insecurity screening questionnaire. 30% of the 430 had "very low food security". Since the pubilcation of this study, a robust Food Rx program has been instituted. All patients now receive a "food prescription" consisting of two 5-10 lb bags of healthy food at clinic. Additionally, food insecure patients at UCSDSRFC are often referred to food pantries. At most clinics where a Food Rx program has not or cannot be implemented, referrals to food pantries are one of few interventions available for food insecure patients. However, there is little research that addresses who is most interested in going to a food pantry and if referred patients actually go. This survey study includes 292 patients surveyed during a 3-month period. This survey included the 6-item USDA food insecurity-screening questionnaire and additional questions about food pantry utilization....</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/6px693t8</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Gushue, Ariane</name>
      </author>
      <author>
        <name>Smith, Sunny</name>
      </author>
    </item>
    <item>
      <title>Fertility preservation and decisional regret in young breast cancer survivors: a longitudinal analysis</title>
      <link>https://escholarship.org/uc/item/6n46m0f3</link>
      <description>Fertility is important to young breast cancer survivors (YBCS). Treatment for breast cancer increases the risk of infertility. Fertility preservation prior to breast cancer treatment aims to improve options for fertility post-treatment. Fertility preservation decisions are challenging for YBCS. In retrospective cohort studies, YBCS that underwent fertility preservation experienced less decisional regret after primary cancer treatment. Objectives and hypotheses: to assess longitudinal changes in decisional regret on fertility preservation following breast cancer diagnosis; to determine if fertility concerns and fertility preservation treatment decisions are related to decisional regret.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/6n46m0f3</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Dewald, Samantha</name>
      </author>
      <author>
        <name>Natarajan, Loki</name>
      </author>
      <author>
        <name>Su, H. Irene</name>
      </author>
    </item>
    <item>
      <title>A clinical survey evaluating the most common factors influencing a parental decision of vaccine refusal, and whether a correlation exists between vaccine refusal and the degree of trust in pediatricians</title>
      <link>https://escholarship.org/uc/item/6k57c1zj</link>
      <description>The practice of vaccine delay and refusal has recently held the attention of the medical community, most notably due to outbreaks of vaccine preventable diseases. It is a loaded subject both for parents/guardians and pediatricians; to the point of pediatricians being more likely to dismiss families who refuse vaccinations for their children. Within the field of pediatrics, this is a topic that poses a threat to the physician-patient relationshp. Studies have shown an increase in vaccine refusals in the last decade; therefore, further examination of the reasons behind this decision remains key in better understanding what drives this decision when made by some parents and guardians. This survey will attempt to cite the most common reasons for this decision directly from parents/guardians, as well as to examine if there is any significant difference between the degree of trust in pediatricians amonst parents/guardians who refuse or delay vaccines when compared to non-refusing parents/guardians....</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/6k57c1zj</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Doroudchi, Ali</name>
      </author>
      <author>
        <name>Crow, Janet</name>
      </author>
      <author>
        <name>Willies-Jacobo, Lindia</name>
      </author>
      <author>
        <name>Crow, Greg</name>
      </author>
    </item>
    <item>
      <title>Respect your elders- age disparities in intracranial pressure monitor use in traumatic brain injury</title>
      <link>https://escholarship.org/uc/item/66j4c748</link>
      <description>The Brain Trauma Foundation recommends intracranial pressure (ICP) monitor placement for patients with severe traumatic brain injury (TBI). Adherence with these guidelines in elderly patients is unknown. We hypothesized that disparities in ICP monitor placement would exist based on patient age.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/66j4c748</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Schupper, Alexander J.</name>
      </author>
      <author>
        <name>Berndtson, Allison E.</name>
      </author>
      <author>
        <name>Smith, Alan</name>
      </author>
      <author>
        <name>Godat, Laura N.</name>
      </author>
      <author>
        <name>Costantini, Todd W.</name>
      </author>
    </item>
    <item>
      <title>Trends in emergency physician opioid prescribing practices during the United States opioid crisis</title>
      <link>https://escholarship.org/uc/item/6650p24j</link>
      <description>Background: prescription opioid related deaths have increased dramatically over the past 17 years. Although emergency physicians (EPs) have not been the primary force behind this rise, previous literature has suggested that EPs could improve their opioid prescribing practices. We designed this study to evaluate the trend in emergency department (ED) opioid prescriptions over time during the US opioid epidemic. Methods: we conducted a retrospective cohort study from July 1, 2012 to June 30, 2018, evaluating all adult patients who presented to two study EDs for a pain-related complaint and received an analgesic prescription upon ED discharge. We compared these data to trends in lay media and medical literature regarding the opioid epidemic. We also evaluated the incidence of repeat ED visits based on the type of analgesic prescriptions provided. Results: opioid prescriptions decreased from 37.76% to 13.29% over the six year study period. This coupled with an increase in non-opioid...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/6650p24j</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Gleber, Ryan</name>
      </author>
      <author>
        <name>Vilke, Gary M.</name>
      </author>
      <author>
        <name>Castillo, Edward M.</name>
      </author>
      <author>
        <name>Brennan, Jesse</name>
      </author>
      <author>
        <name>Oyama, Leslie</name>
      </author>
      <author>
        <name>Coyne, Christopher J.</name>
      </author>
    </item>
    <item>
      <title>Defining the three-dimensional deformity in slipped capital femoral epiphysis</title>
      <link>https://escholarship.org/uc/item/4nk7h213</link>
      <description>The purpose of this study was to define a novel angle measure (theta) characterizing true slipped capital femoral epiphysis (SCFE) deformity; use theta to differentiate between SCFE hips, contralateral unaffected hips, and normal hips; and to compare theta to the Southwick slip angle (SSA). 3DCT reconstructions of the pelvis and femurs were obtained and pelvic position was standardized. The center point and direction vector of the femoral epiphysis was determined. The femoral neck axis was defined. The angle between the femoral neck axis and epiphysis vector defined the 3D angle of deformity (theta). The 3D translation of the femoral epiphysis, measured as a percentage of femoral neck diameter, was measured in three planes. The average theta angle was significantly greater in SCFE hips (44.9±22.5°) compared to control (14.5±8.8°) or normal (14.0±6.5°) hips (p&amp;lt;0.001). There was no significant difference in theta angle between control and normal hips (p=0.83). Theta angle correlated...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/4nk7h213</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Valdovino, Alan G.</name>
      </author>
      <author>
        <name>Bland, Daniel C.</name>
      </author>
      <author>
        <name>Jeffords, Megan E.</name>
      </author>
      <author>
        <name>Bomar, James D.</name>
      </author>
      <author>
        <name>Newton, Peter O.</name>
      </author>
      <author>
        <name>Upsani, Vidyadhar V.</name>
      </author>
    </item>
    <item>
      <title>Determine the feasibility of a customizable Ultrasound gel phantom for production and distribution to the masses: A cheaper, realistic gel phantom will allow more accessibility and improved training for practitioners</title>
      <link>https://escholarship.org/uc/item/4mh6837g</link>
      <description>Simulation has become an integral part of learning new procedures and staying adept at skills already learned. Ultrasound (US) guided peripheral IV (PIV) needle insertion is a skill necessary for EM, Anesthesia, and general practice nurses and physicians. Medical schools, teaching hospitals, and community hospitals universally use simulation amongst their practitioners. Ultrasound POC use is increasing in Emergency Department (ED) and other hospital areas. Most institutions have formalized training to teach residents and nurses proper techniques for POC US use. Training models can vary from commercially available ones costing thousands of dollars to home-made ones that have a short life-span and suboptimal viewing characteristics. 1 Patient safety has been a driving force in changing medical training. "To Err is Human", a landmark study published in 1999 estimated 3% of injuries to hospital patients are caused by medical errors, resulting in between 44,000-98,000 deaths per year....</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/4mh6837g</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Rashid, Sabir</name>
      </author>
    </item>
    <item>
      <title>Patients who leave the emergency department without being seen and their follow-up behavior: a retrospective descriptive analysis</title>
      <link>https://escholarship.org/uc/item/4jq8c75n</link>
      <description>Past studies suggest that patients who leave without being seen by a physician (LWBS) from a hospital’s emergency department (ED) represent a quality and safety concern, and thus LWBS rates have often been used as an ED performance metric. There are few recent studies, however, that have examined the characteristics of the LWBS population at hospitals in the United States.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/4jq8c75n</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Li, David R.</name>
      </author>
      <author>
        <name>Brennan, Jesse J.</name>
      </author>
      <author>
        <name>Kreshak, Allyson A.</name>
      </author>
      <author>
        <name>Castillo, Edward M.</name>
      </author>
      <author>
        <name>Vilke, Gary M.</name>
      </author>
    </item>
    <item>
      <title>Web-based pharmacology cases for Cardiovascular System 1 and Renal System 1</title>
      <link>https://escholarship.org/uc/item/4cr5q7mg</link>
      <description>Undergraduate medical education is constantly evolving to develop new, effective, engaging teaching methods. An integrated medical school curriculum correlates the basic and clinical sciences beginning in the first year in order to engage students, develop clinical reasoning skills, and prepare them for their clinical experiences. Contextualization, in which clinical case examples are used to illustrate basic science principles, is one strategy used to achieve this goal. In addition to changes in the structure of medical school curricula, the platforms by which educational material is delivered are also rapidly changing. Web-based applications, including podcasts and virtual interactive cases, provide endless opportunities to present information in efficient and interesting formats and encourage self-directed learning by students. Pharmacology is an area of preclerkship education that is particularly challenging to medical students. One reason for this is the fact that students...</description>
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      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Dern, Kathryn</name>
      </author>
    </item>
    <item>
      <title>Implementation of an educational exercise to enhance clinical reasoning in third year medical students</title>
      <link>https://escholarship.org/uc/item/4cq557qj</link>
      <description>Clinical reasoning (CR) is essential to a physician's practice of medicine. Although there have clear efforts to incorporate CR into the pre-clinical curriculum at UCSD-SOM, there is a lack of formal CR education during rotations. Thus, the Clinical Reasoning Exercise (CRE) was designed for third year medical students on the inpatient internal medicine service. The CRE is an educational exercise that provides step-by-step guidance through the diagnostic process by utilizing three principles--problem representation, diagnostic schema, and illness scrips. Supplementary materials include narrated PowerPoint/YouTube tutorials (for both students and faculty) as well as an example completed CRE for student reference. The CRE was piloted with six students rotating the Veteran's Association (VA) in February 2019. Students were met in small groups (2-3) to review general aspects and logistics. After the one-month long inpatient rotation, students were sent the link to an anonymous survey....</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/4cq557qj</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Cochran, Megan</name>
      </author>
    </item>
    <item>
      <title>Intervertebral disc kinematics in active duty marines with and without lumbar spine pathology</title>
      <link>https://escholarship.org/uc/item/3nm575zx</link>
      <description>Military members are required to carry heavy loads frequently during training and active duty combat. We investigated if operationally relevant axial loads affect lumbar disc kinematics in forty-one male active duty Marines with no previous clinically diagnosed pathology. Marines were imaged standing upright with and without load. From T2-weighted magnetic resonance images, IVD health and kinematic changes between loading conditions and across lumbar levels were evaluated using two-way repeated measures analysis of variance tests. IVD kinematics with loading were compared between individuals with and without signs of degeneration on imaging. Linear regression analyses were performed to determine associations between IVD position and kinematic changes with loading. Fifty-eight percent (118/205) of IVDs showed evidence of degeneration and 3% (7/205) demonstrated a disc bulge. IVD degeneration was not related to posterior annular position (p&amp;gt;0.205). Changes in sagittal intervertebral...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/3nm575zx</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Onodera, Keenan</name>
      </author>
      <author>
        <name>Berry, David B.</name>
      </author>
      <author>
        <name>Shahidi, Bahar</name>
      </author>
      <author>
        <name>Kelly, Karen R.</name>
      </author>
      <author>
        <name>Ward, Samuel R.</name>
      </author>
    </item>
    <item>
      <title>Using high-fidelity simulation to teach neurological emergency and neurocritical care skills: A systematic review of the literature</title>
      <link>https://escholarship.org/uc/item/3gr3s7kw</link>
      <description>This article analyzes the current available literature on high-fidelity simulation as an educational tool in teaching acute neurology and neurocritical care skills to trainees. Twenty-five studies were found to be published in peer-reviewed journals. While every study had a common target of educating learners on appropriate acute neurology evaluation, diagnosis, and management, there exists significant heterogeneity in the chosen topics, implemented procedures, and assessments of learner outcomes. Overall findings suggest that there is considerably significant evidence for the effectiveness and utility of simulation-based education when it comes to the teaching of acute and critical neurological emergencies to trainees and even practicing providers. Existing literature is summarized, current trends are discussed, and recommendations for areas of future research are included.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/3gr3s7kw</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Wu, Victoria</name>
      </author>
      <author>
        <name>Kansal, Leena</name>
      </author>
      <author>
        <name>Minokadeh, Anushirvan</name>
      </author>
      <author>
        <name>Gonzalez Gonzalez, Cynthia</name>
      </author>
    </item>
    <item>
      <title>Parental polst preferences for pediatric patients enrolled in palliative home care</title>
      <link>https://escholarship.org/uc/item/3bp802mr</link>
      <description>Palliative care and advanced health directives, particularly the Physician’s Orders for Life Sustaining Treatment (POLST), play significant roles in the management of seriously ill children and those with chronic medical conditions. Multiple studies have demonstrated improved patient quality of life and family sense of autonomy and control when advance health directives are implemented, yet little is known about actual end‐of-life‐care choices parents make. The goal of this project was to examine parental preferences for end‐of‐life care among patients enrolled in a pediatric palliative home care program (PPHCP) or hospice who have completed a POLST.  .</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/3bp802mr</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Rosen, Jared</name>
      </author>
    </item>
    <item>
      <title>Investigation of enrichment programs at juvenile detention facilities in San Diego County</title>
      <link>https://escholarship.org/uc/item/3b82f9t4</link>
      <description>Enrichment activities are known to enhance youth development, and are especially beneficial for at-risk youth who have not consistently had the social capital to receive such enrichment throughout the critical periods of their development. The National Institute of Justice has published many studies demonstrating the benefit of enrichment activities for disadvantaged youth. Enrichment activities promote self-esteem and sense of discipline and well-being, which impacts mental health and risk taking behaviors such as substance abuse. With the goal of achieving the aforementioned impact, juvenile detention centers offer enrichment programs as part of the rehabilitation process. My goal for this project was to further investigate the availability, equity and impact of such programs on mental health outcomes for at risk youth, I completed a needs assessment. The following needs assessment report summarizes my findings.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/3b82f9t4</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Labastide, Angèle Shari Helen</name>
      </author>
    </item>
    <item>
      <title>Patient-derived organoid systems for the study of castrate-resistant metastatic prostate cancer</title>
      <link>https://escholarship.org/uc/item/37q536r1</link>
      <description>Bone metastases of prostate cancer continue to elude effective clinical management world-wide. A newly developed xenograft model, PCSD1, is a pre-clinical therapeutic development and testing platform to understand the mechanisms of resistance to androgen deprivation therapy of bone metastatic prostate cancer. Prostate cancer is a heterogeneous disease for which it is especially important to study models that represent the range of different patients. However, of the patient samples investigated by Christina Jamieson’s lab at UCSD, only 5 out of 20 (25%) were able to successfully create xenografts. The hypothesis I tested is that metastatic cells that have failed to xenograft into a patient-derived tumor xenograft mouse model will be able to successfully survive in vitro in an organoid culture system. The goals of my research were twofold: to successfully develop organoid cultures for both cells that have successfully and unsuccessfully xenografted into the mouse model and to perform...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/37q536r1</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Zhu, William</name>
      </author>
    </item>
    <item>
      <title>Optimization of laboratory services and education at the UCSD student run free clinic project during electronic health record and laboratory information systems integration</title>
      <link>https://escholarship.org/uc/item/2x4029rz</link>
      <description>Clinical notes, consults, vital signs, labs, and more are expected to be a part of a patient’s electronic file, so that they can be easily and quickly looked up to provide better patient care. The UCSD Student‐Run Free Clinic Project (SRFCP) implemented Electronic Health Records (Epic) in 2013. However, the laboratory used by the free clinics had not been integrated electronically. Therefore, the free clinics had been entering lab results into EPIC via manual data entry for four years. In 2017, the UCSD Epic Information Technology team, including the Ambulatory Offices’ Chief Medical Information Officer, decided that it was a UCSD Health Sciences priority to integrate Quest labs into Epic. This required a significant amount of retraining, writing new workflows, improving processes, re‐thinking the role of the free clinic lab manager, optimizing education, and ensuring the correct provider receives results in a timely fashion in the UCSD SRFCP setting. This ISP assessed the laboratory...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/2x4029rz</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Peng, Brain</name>
      </author>
    </item>
    <item>
      <title>Characteristics and outcomes of geriatric patients who were screened through the Geriatric Emergency Nurse Initiative Expert (GENIE) risk screening and referral system</title>
      <link>https://escholarship.org/uc/item/2jz8k9v7</link>
      <description>With a rapidly growing older adult population in the United States, the importance of age-appropriate care in the emergency department (ED) is becoming increasingly recognized. The University of California, San Diego (UCSD) La Jolla ED has adopted the use of a specialized health and welfare screening and referral system in its Senior Emergency Care Unit (SECU) to address the unique needs of older adult patients. Trained geriatric nurses screen patients and positive screens generate automatic referrals. Between December 1, 2016 and October 31, 2018 a total of 974 eligible patients were screened. Of these, 354 patients had one or more positive screens and received referrals. A retrospective chart review was used to examine clinical and demographic characteristics of patients to evaluate outcomes of the screening and referral system.  Statistical analysis include: two sample t-tests to compare average age between groups; chi-square and likelihood ratio tests to compare demographic...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/2jz8k9v7</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Stumhofer, Gretchen</name>
      </author>
      <author>
        <name>Tolia, V. M.</name>
      </author>
      <author>
        <name>Vilke, Gary M.</name>
      </author>
      <author>
        <name>Castillo, Edward M.</name>
      </author>
    </item>
    <item>
      <title>Off-pump versus on: long-term outcomes after coronary artery bypass in a veteran population</title>
      <link>https://escholarship.org/uc/item/26g618hh</link>
      <description>We sought to investigate long-term outcomes after revascularization with and without use of cardiopulmonary bypass, and hypothesized off-pump would be comparable to on-pump. Our primary outcome of interest was survival, and secondary outcomes included need for reintervention with new coronary stent, or new diagnosis of myocardial infarction (MI) occurring any time after surgery during the 8-12 year follow up period.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/26g618hh</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Parmeshwar, Nisha</name>
      </author>
    </item>
    <item>
      <title>Identification of gestational age-dependent changes in ExRNA expression across normal human pregnancy</title>
      <link>https://escholarship.org/uc/item/23b4h1k2</link>
      <description>&lt;p&gt;To develop an atlas of the serum profile of miRNA in normal human pregnancy, and compare variability across gestation, day-to-day variability, and diurnal variability&lt;/p&gt;&lt;p&gt;To explore whether the ability to detect gestational-age specific changes is dependent on methodology.&lt;/p&gt;</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/23b4h1k2</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Verma, ian</name>
      </author>
    </item>
    <item>
      <title>Evaluating current and potential clinical sites: a spatial analysis of the UCSD Student-Run Free Clinic Project: a student's guide</title>
      <link>https://escholarship.org/uc/item/20g1j83s</link>
      <description>After 18 years of service in the same location, the UCSD Free Clinic Project (Free Clinic) had to close one its four clinic sites. Several hundred patients were faced with the challenge of commuting long distances to another clinic, and even losing access to car. Although unfortunate, this became an opportunity for the Free Clinic to examine where its patients live, the distances they travel to clinic, and determine new locations for a clinic. To complete this examination, the Free Clinic performed a spatial analysis--mapping patients and clinic locations--using specialized Geographic Information Systems (GIS) software.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/20g1j83s</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Coblentz, Ian</name>
      </author>
    </item>
    <item>
      <title>Potential treatments for Danon disease</title>
      <link>https://escholarship.org/uc/item/1sq9j86f</link>
      <description>Danon disease is a congenital X-linked hypertrophic cardiomyopathy that results from mutations in LAMP2, a transmembrane lysosomal protein necessary for autophagy. The disease presents in childhood or adolescence, and life expectancy is 19 for men and 34 for women. Although Danon disease is rare, no specific therapy based on its biology is currently known. Recent in vitro studies using mouse by the Cherqui Lab have shown evidence supporting hematopoetic stem cell transplant as a novel treatment option for cystinosis. Cystinosis is a metabolic disease that arises from mutations in a transmembrane lysosomal protein - cystinosin (CTNS gene). Detailed in vitro and in vivo studies have shown that rescue of the phenotype occurs because wildtype macrophages derived from the transplanted wildtype hematopoietic stem cells can transfer lysosomes containing wildtype cystinosin directly to Ctns-deficient cells in multiple organs of the host Ctns -/- mice. Because Danon disease also arises...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/1sq9j86f</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Khan, Sohini</name>
      </author>
      <author>
        <name>Hashem, Sharin</name>
      </author>
      <author>
        <name>Cherqui, Stephanie</name>
      </author>
      <author>
        <name>Evans, Sylvia</name>
      </author>
      <author>
        <name>Adler, Eric D.</name>
      </author>
    </item>
    <item>
      <title>Current management of succinate dehydrogenase deficient gastrointestinal stromal tumors</title>
      <link>https://escholarship.org/uc/item/1n04t463</link>
      <description>Gastrointestinal stromal tumors (GIST) are increasingly recognized as having diverse biology. With the development of tyrosine kinase inhibitors molecularly matched to oncogenic KIT and PDGFRA mutations, GIST have become a quintessential model for precision oncology. However, about 5-10% of GIST lack these driver mutations and are deficient in succinate dehydrogenase (SDH), an enzyme that converts succinate to fumarate.  SDH deficiency leads to accumulation of succinate, an oncometabolite that promotes tumorigenesis. SDH- deficient GIST are clinically unique in that they generally affect younger patients and are associated with GIST- paraganglioma hereditary syndrome, also known as Carney-Stratakis Syndrome. SDH-deficient GIST are  generally resistant to tyrosine-kinase inhibitors, the standard treatment for advanced or metastatic GIST. Thus, surgical resection is the mainstay of treatment for localized disease, but recurrence is common. Clinical trials are currently underway...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/1n04t463</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Neppala, Pushpa</name>
      </author>
      <author>
        <name>Banerjee, Sudeep</name>
      </author>
      <author>
        <name>Fanta, Paul T.</name>
      </author>
      <author>
        <name>Yerba, Mayra</name>
      </author>
      <author>
        <name>Porras, Kevin A.</name>
      </author>
      <author>
        <name>Burgoyne, Adam M.</name>
      </author>
      <author>
        <name>Sicklick, Jason K.</name>
      </author>
    </item>
    <item>
      <title>Neurology clerkship review</title>
      <link>https://escholarship.org/uc/item/1mj6p19r</link>
      <description>Slides presenting a top-down, not "pattern-recognition," approach to decision-making in a clinical neurology setting.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/1mj6p19r</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Carlson, David</name>
      </author>
    </item>
    <item>
      <title>Warm Handoff: Fact or Fiction?</title>
      <link>https://escholarship.org/uc/item/1j7138tk</link>
      <description>&lt;p&gt;1. Compare characteristics of patients in which a BHP was involved in any manner in apatient’s visit to those who did not have any BHP involvement in their visit.&lt;/p&gt;&lt;p&gt;2. Compare follow-through rates after referral to psychotherapy for patients who didversus did not have a warm handoff (i.e., face-to-face interaction with a BHP) at the timeof the patient’s visit to a PCP&lt;/p&gt;</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/1j7138tk</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Lambeck, Alexandra</name>
      </author>
    </item>
    <item>
      <title>The circle of Willis predicts the antihypertensive effects of carotid artery stenting: 12 month follow up</title>
      <link>https://escholarship.org/uc/item/14r1t8zg</link>
      <description>Stroke is one of the leading causes of death and morbidity in the United States. Various modifiable risk factors have been identified, which elevate the risk of stroke. Two such risk factors include hypertension and carotid artery stenosis. Moreover, carotid artery atherosclerosis, even when asymptomatic or when subclinical stenosis is present, has been shown to increase the risk of future stroke. As such, proper treatment of carotid artery stenosis and hypertension plays a critical role in the future reduction of stroke incidence.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/14r1t8zg</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Porras, Kevin</name>
      </author>
    </item>
    <item>
      <title>MRI neuroimaging in the evaluation of post-laminectomy pain syndrome</title>
      <link>https://escholarship.org/uc/item/10015849</link>
      <description>Post-laminectomy pain syndrome refers to persistent leg and/or lumbar back pain after a surgical procedure. The pathophysiology of this syndrome is complex, as often the operation was  technically successful. Evaluation with MRI plays a crucial role in the assessment of post- laminectomy pain syndrome, as it provides soft tissue resolution for evaluation for common post- surgical pain generators, including recurrent posterior disc disease and associated narrowing of  the spinal canal, lateral recess or neural foramina.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/10015849</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Trujillo, Daniel</name>
      </author>
    </item>
    <item>
      <title>Anesthesia student survival guide</title>
      <link>https://escholarship.org/uc/item/0ww3k4c3</link>
      <description>At UC San Diego medical school, third year medical students’ exposure to Anesthesia is often as part of a two-week selective during their surgery rotation. Students are told to read up on Miller or Bareish (not for the faint of heart) to understand the foundational knowledge for the rotation. Fourth year medical students often feel like there should be a concise introductory document to help students before the rotation. This document is to provide a brief introduction to the field of anesthesia and ensure students feel more prepared prior to the rotation. This document is intended to be modified and altered as other students find the information outdated or irrelevant to the Anesthesia rotation.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/0ww3k4c3</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Samuel, Nebiyou</name>
      </author>
    </item>
    <item>
      <title>Gender micro-inequities in medical education</title>
      <link>https://escholarship.org/uc/item/06g4z6m2</link>
      <description>To explore the topic of gender micro‐inequities, both on a personal level and on a professional level. To evaluate literature on the topic. This includes evaluating the different ways to study this topic (survey, focus group, longitudinal interviews, etc), as well as the specific populations studied and critically consider the positives and negatives of the different methods. To plan and give a professional lecture/webinar, including seeking feedback and evaluation.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/06g4z6m2</guid>
      <pubDate>Thu, 29 Oct 2020 00:00:00 +0000</pubDate>
      <author>
        <name>Whitchurch, Theresa</name>
      </author>
    </item>
    <item>
      <title>Rigid segmental cervical spine instrumentation is safe and efficacious in younger children</title>
      <link>https://escholarship.org/uc/item/9dj3n4mz</link>
      <description>The utilization of cervical spine instrumentation in the young pediatric patient in not well reported. This study presents outcomes and complications of cervical spine instrumentation in patients who underwent cervical spine fusion surgery before age 10. Radiographic and clinical data were collected on all patients who underwent cervical spine surgery with instrumentation at a single institution between January 1, 2006 and March 21, 2015. Patients were ≤ years of age at the time of surgery with any cervical spine deformity/injury diagnosis. Patient demographics, details on cervical spine diagnosis, procedural data, imaging data, and post-operative follow up data were collected. Twenty children met the criteria and were included in the study with a mean follow-up of 10.6 months (3 mo to 2 years). Initial indication for cervical spine correction surgery included: deformity (7 cases), trauma (6 cases), instability (3 cases), stenosis (2 cases), rotary subluxation (1 case), and infection...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/9dj3n4mz</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Mitchell, Ana</name>
      </author>
      <author>
        <name>Upasani, Vidyadhar V.</name>
      </author>
      <author>
        <name>Bartley, Carrie E.</name>
      </author>
      <author>
        <name>Newton, Peter O.</name>
      </author>
      <author>
        <name>Yaszay, Burt</name>
      </author>
    </item>
    <item>
      <title>Implementation of web-based educational tool to promote clinical reasoning in pbl</title>
      <link>https://escholarship.org/uc/item/99c2f44p</link>
      <description>Clinical reasoning is the complex cognitive analysis employed by physicians during the medical decision making process. This is first introduced in the problem-based learning (PBL) course in the preclinical medical school curriculum with the PBL facilitator playing a critical role in meeting these educational goals. However, factors, such as the instructor's clinical experience and teaching style, will have an impact the group's engagement in the clinical reasoning process. Thus, the clinical reasoning tool was developed to address this variability, with the goal of strengthening small group engagement in clinical reasoning during PBL. The clinical reasoning tool (CRT) is an online educational application, which provides a framework for the process of developing and analyzing the differential diagnosis for a clinical case. It was assigned as a self-directed learning assignment to one student per small group for selected second-year PBL cases during one academic quarter. There...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/99c2f44p</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Chandra, Neha</name>
      </author>
    </item>
    <item>
      <title>A prospective study of stingray injury and envenomation outcomes</title>
      <link>https://escholarship.org/uc/item/8z3234wt</link>
      <description>Stingray injuries result in thousands of emergency department visits annually. This study aimed to assess the complication rate and outcome of field treatment with hot water immersion. This was an on-site, prospective, observational study. Subjects were enrolled after having been stung by a stingray. A trained researcher obtained the following information: age, sex, health conditions and medications, and wound description. The efficacy of hot water immersion on pain was recorded. Patients were contacted on post-injury days 3, 7, and 14 for follow up. 22 subjects were included. No obvious foreign bodies were observed in wounds. 10 subjects were treated with hot water immersion and povidone-iodine, 12 with hot water immersion alone. Ongoing symptoms or complications were notes at 3-day follow-up in 6 of 22 subjects (27.3%). One subject was diagnosed with cellulitis on post-sting day 8, and was treated with antibiotics. Ongoing symptoms or complications were reported more commonly...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/8z3234wt</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Myatt, Toby</name>
      </author>
    </item>
    <item>
      <title>Medical professionals in remote and extreme environments : a mission to Mars</title>
      <link>https://escholarship.org/uc/item/8n766294</link>
      <description>To give a representative overview of medical professionals working in today's remote and extreme environments, we consider the following teams and organizations: Expeditions on 8000m peaks led by accredited guides of the American Mountain Guides Association (AMGA) or International Federation of Mountain Guides Association (IFMGA). Everest Base Camp Medical Clinic (Everest ER) in Nepal. US Antarctic Program (USAP). Medical Departments aboard US Navy ships and submarines. US Special Operations Command (SOCOM) Corpsmen and Medics. US Navy Diving Medical Officers. Crew Medical Officers (CMO's) aboard the International Space Station After reviewing the practice environments and medical training of the various teams, we consider the medical qualifications of a hypothetical future team embarking on a mission to a particularly remote and extreme environment, a human spaceflight mission to the surface of Mars.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/8n766294</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Hsu, Michael M.</name>
      </author>
      <author>
        <name>Coffey, Christanne H.</name>
      </author>
      <author>
        <name>Witucki, Peter</name>
      </author>
      <author>
        <name>Sloane, Christian</name>
      </author>
    </item>
    <item>
      <title>Lower-body negative pressure decreases noninvasively measured intracranial pressure and internal jugular vein cross-sectional area during head-down tilt</title>
      <link>https://escholarship.org/uc/item/8n59j5gr</link>
      <description>Long-term spaceflight induces a near visual acuity change in ~50% of astronauts. In some crew members, postflight cerebrospinal fluid (CSF) opening pressures by lumbar puncture are as high as 20.9 mmHg; these members demonstrated optic disc edema. CSF communicates through the cochlear aqueduct to affect perilymphatic pressure and tympanic membrane motion. We hypothesized that 50 mmHg of lower-body negative pressure (LBNP) during 15° head-down tilt (HDT) would mitigate elevations in internal jugular vein cross-sectional area (IJV CSA) and intracranial pressure (ICP). Fifteen healthy adult volunteers were positioned in sitting (5 min), supine (5 min), 15° HDT (5 min), and 15° HDT with LBNP (10 min) postures for data collection. Evoked tympanic membrane displacements (TMD) quantified ICP noninvasively. IJV CSA was measured using standard ultrasound techniques. ICP and IJV CSA increased significantly from the seated upright to the 15° HDT posture (P &amp;lt; 0.05), and LBNP mitigated...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/8n59j5gr</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Watkins, William</name>
      </author>
    </item>
    <item>
      <title>An exploration of narrative medical writing</title>
      <link>https://escholarship.org/uc/item/8n40m6sz</link>
      <description>A narrative exploration of death from the view of a medical student on rotation in intensive care units.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/8n40m6sz</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Wackerbarth, Jesse</name>
      </author>
    </item>
    <item>
      <title>Radiologic anatomy</title>
      <link>https://escholarship.org/uc/item/8fq504xf</link>
      <description>My ISP project is a new educational tool in the form of a MedPics expansion dedicated to imaging of normal human anatomy. It serves to address: 1) the dearth of radiology exposure and education in the new Integrated Studies Curriculum; 2) the increasing need for imaging knowledge and skills; 3) some of the limitations of the current cadaveric anatomy education at UCSD School of Medicine. The project has two goals: 1) to re-integrate radiology into the pre-clinical curriculum of UCSD School of Medicine; 2) to strengthen and complement the existing anatomy curriculum of UCSD School of Medicine.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/8fq504xf</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Malinak, Joanne Bae</name>
      </author>
    </item>
    <item>
      <title>Analysis of the impact of SET meetings on curricular changes</title>
      <link>https://escholarship.org/uc/item/8cm8c0dq</link>
      <description>In 2010 the UCSD School of Medicine added student evaluation teams (SET) to the medical education review process in addition to previously implemented student submitted online evaluations. SET groups comprise of sixteen randomly students who are assigned to evaluate at least one course during the year. Other participants in the meeting include respective course directors, thread directors, clinical educators, course assistants, and administrative deans. Students are encouraged to provide constructive feedback throughout the session and faculty are encouraged to listen carefully and ask clarifying questions as needed. The impact of SET on curricular changes has not been evaluated previously. This project aimed to study the impact of SET on curricular change in both the short term and long term for core courses in the second year medical school curriculum.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/8cm8c0dq</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Rabadia, Soniya</name>
      </author>
    </item>
    <item>
      <title>Retrospective review of MRI data to characterize shoulder pathoanatomy in patients with spinal cord injury</title>
      <link>https://escholarship.org/uc/item/7mt2k90p</link>
      <description>Wheelchair-bound paraplegic patients are especially prone to rotator cuff lesions as they excessively load their shoulder joint and muscles. To properly manage their care and to ensure that they do not suffer loss of shoulder functionality, it is essential to understand the physiological and anatomical changes to the rotator cuff muscle and underlying shoulder joint structure in this particular groups of patients. We retrospectively reviewed MRI data obtained on paraplegic and able-bodied patients and did not find any significant changes in shoulder pathoanatomy. The study did have several limitations which could be further investigated to elucidate a few conflicting findings.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/7mt2k90p</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Xu, Conway</name>
      </author>
    </item>
    <item>
      <title>Contribution of cardiac implantable electronic devices (CIEDs) to thrombus formation in patients with chronic thromboembolic pulmonary hypertension (CTEPH)</title>
      <link>https://escholarship.org/uc/item/7bd2c5j3</link>
      <description>Chronic thromboembolic pulmonary hypertension (CTEPH) is a debilitating disease, now potentially curable with the advent of pulmonary thromboendarterectomy (PTE). This study aimed to identify the prevalence of cardiac implantable electronic devices (CIEDs) in the PTE population and describe associated disease burden. The contribution of CIEDs to thrombosis in this patient population has not been previously studied. The charts of 982 CTEPH patients, who underwent PTE between January 1, 2009 and December 31, 2015 at UC San Diego (UCSD) Medical Center, were reviewed for pacemaker or ICD leads implanted prior to surgery. All statistical analyses were completed using SPSS software. Continuous variables were analyzed with t-tests for normally distributed data; categorical variables were compared with chi-squares. Among 982 total CTEPH patients who underwent PTE, 14 had pacemakes and 3 had ICD leads, for a total of 17 CIEDs and a prevalence of 1.7%. Of these 17 CIEDs, 6 devices were...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/7bd2c5j3</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Nayak, Rohith</name>
      </author>
      <author>
        <name>Fernandes, Timothy M.</name>
      </author>
      <author>
        <name>Auger, William R.</name>
      </author>
      <author>
        <name>Praetorius, G. Victor</name>
      </author>
      <author>
        <name>Madani, Michael M.</name>
      </author>
      <author>
        <name>Birgersdotter-Green, Ulrike</name>
      </author>
    </item>
    <item>
      <title>Designing exercise and muscle strengthening videos to increase physical therapy compliance and effectiveness in non-operative pediatric orthopedic patients</title>
      <link>https://escholarship.org/uc/item/78v7n7hw</link>
      <description>This project set out to create a series of short narrated videos displaying proper stretching and strengthening techniques for the treatment of non-operative muscular complaints in pediatric patients. Three headings of disorder were addressed: core strengthening, patellofemoral pain, and shoulder injury. Within each of these categories, a number of short videos were produced using several actors demonstrating correct technique. Narration was then added to describe what was occurring onscreen and prevent incorrect form. A total of 32 videos were produced and made available for free on the Rady Children's Hospital 360 Sports Medicine website (http://www.rchsd.org/programsservices/sports-medicine/) for easy access by physicians, physical therapists, patients and their parents.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/78v7n7hw</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Burns, Luke</name>
      </author>
    </item>
    <item>
      <title>The multidisciplinary treatment of eating disorders focused clinical multidisciplinary independent study project (FCM-ISP)</title>
      <link>https://escholarship.org/uc/item/6xd3p5vk</link>
      <description>Eating disorders are a diverse group of psychiatric diseases affecting millions of youth in the United States. Because these disorders can often be chronic illnesses with significant physical, psychological, and social consequences, early intervention is critical for a good prognosis. This requires skilled primary care physicians to recognize signs of eating disorders and refer patients to the appropriate level of care. The purpose of this project was to gain clinical exposure to eating disorders and their treatment to become a better-informed future general pediatrician who can identify and initiate management of these disorders.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/6xd3p5vk</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Lee, Sarah</name>
      </author>
    </item>
    <item>
      <title>Modernizing surgical education : motion tracking of hand movements during surgical knot tying</title>
      <link>https://escholarship.org/uc/item/6t83563g</link>
      <description>Surgical training has traditionally been based on an apprenticeship model whereby a resident trainee will acquire surgical competencies through accumulated experience and long hours spent observing a more experienced supervising surgeon in the operating room. However, this method has been criticized for being too subjective, too costly in human resources, time-consuming, and not accurately representing technical skill. Of note, a study showed that only 34% of surgical trainees report feeling they have sufficient training in basic surgical skills. As a result, there has been significant interest in developing cost-effective methods of objectively assessing technical skill in surgery, both for the purposes of credentialing and for formative feedback.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/6t83563g</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Jiang, Michael</name>
      </author>
    </item>
    <item>
      <title>Set's vs online evaluations for medical school pre-clinical courses</title>
      <link>https://escholarship.org/uc/item/6s76f3k4</link>
      <description>Starting in 2010, UCSD School of Medicine switched over to an organ systems‐based curriculum, and with this switch also came a new way of collecting student feedback on courses called the SET (Student Evaluation Team). Traditionally, feedback was collecting mainly through online course and instructor evaluations. However, this method of collecting feedback does not allow for conversation and/or problem solving with the course directors. Additional qualitative data gathered from SET meetings helps validate, explain, and reinterpret the quantitative data gathered in the online evaluations. In addition, qualitative responses to open‐ended questions and the ensuing discussions can result in serendipitous findings, leading to new avenues to approach that the researcher may not have originally thought of (Hsieh et al., 2014).</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/6s76f3k4</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Chang, Alexander</name>
      </author>
    </item>
    <item>
      <title>Patient-specific 3D models aid planning for triplane proximal femoral osteotomy in slipped capital femoral epiphysis</title>
      <link>https://escholarship.org/uc/item/6p43g5vj</link>
      <description>Purpose slipped capital femoral epiphysis (SCFE) can result in a complex three-dimensional (3D) deformity of the proximal femur. A three-plane proximal femoral osteotomy (TPFO) has been described to improve hip mechanics. The purpose of this study was to evaluate the benefits of using 3D print technology to aid in surgical planning.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/6p43g5vj</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Cherkasskiy, Lillia</name>
      </author>
      <author>
        <name>Caffrey, J. P.</name>
      </author>
      <author>
        <name>Szewczyk, A. F.</name>
      </author>
      <author>
        <name>Cory, E.</name>
      </author>
      <author>
        <name>Bomar, J. D.</name>
      </author>
      <author>
        <name>Farnsworth, C. L.</name>
      </author>
      <author>
        <name>Jeffords, M.</name>
      </author>
      <author>
        <name>Wenger, D. R.</name>
      </author>
      <author>
        <name>Sah, R. L.</name>
      </author>
    </item>
    <item>
      <title>Spanish language proficiency in bilingual providers</title>
      <link>https://escholarship.org/uc/item/6n72z16b</link>
      <description>The United States has steadily become more language diverse. This effect is highly visible in San Diego, where approximately 25% of the population prefers to speak Spanish. Language proficiency in bilingual providers has been identified as a concern amongst patients who speak languages other than English. Providers who are not fully bilingual, but do not use the interpreter services provided by the hospitals are putting their patients at risk for poorer outcomes. Interpreters are being underused in interactions with patients with limited English proficiency (LEP). Therefore, identifying providers who are either bilingual or motivated to become bilingual would improve the care of LEP patients greatly.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/6n72z16b</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Dilip, Monisha</name>
      </author>
    </item>
    <item>
      <title>The biopsychosocial evaluation of female sexual dysfunction</title>
      <link>https://escholarship.org/uc/item/6gj1476p</link>
      <description>It is reported that more than 10-20% of women in the United States have sexual health problems involving desire, arousal, orgasm, and/or pain associated with personal distress or bother. Historically, these issues were managed primarily by mental health professionals and were largely ignored by the medical community. Male sexual dysfunction, on the other hand, found its place within the field of urology. With the advent of the FDA approved sildenafil as a safe and effective treatment for men with erectile dysfunction in 1998, women began seeking medical attention and demanding equal therapies for their own unaddressed sexual health concerns.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/6gj1476p</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Da Silva, Stephanie</name>
      </author>
    </item>
    <item>
      <title>Improving community mental health access through implementation of a universal depression screening in a Student-Run Free Clinic</title>
      <link>https://escholarship.org/uc/item/63t0c9h6</link>
      <description>Major depression is one of the most common, debilitating, and treatable psychiatric disorders in America, yet depression is significantly under-identified among low-income and uninsured populations. The USPSTF recommends routine depression screening in the setting of primary care when mental health support resources are available. The purpose of this project was to implement a universal depression screening in Student-Run Free Clinics (SRFCs) to improve identification and treatment of depression in patients receiving primary care</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/63t0c9h6</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Ames, Angharad</name>
      </author>
    </item>
    <item>
      <title>"Achieving health &amp;amp; wellness curriculum--becoming a youth health promoter" curriculum development</title>
      <link>https://escholarship.org/uc/item/5qs1q6qd</link>
      <description>The "Achieving Health &amp;amp; Wellness--Becoming a Youth Health Promoter" aka "Health and Health Professions: Becoming a youth health promoter" class is a 7th and 8th grade course developed at Lemon Grove Academy for the Sciences and Humanities, that covers a wide range of topics related to personal and community health and wellness. The focus of the elective is for the young person to become a Youth Health Promoter--at the level of self, school, family, community and society. Students are empowered with tools and knowledge to help maintain their own wellness, and become leaders in promoting the wellness of those around them. The course has been well received by students at the school, and the course developers desired to have all the materials and teaching methods put into a form that would allow dissemination and implementation at other schools for the benefit of more students and educators. The purpose of this Independent Study Project was to synthesize all the materials associated...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/5qs1q6qd</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Thomas, Selina</name>
      </author>
    </item>
    <item>
      <title>Platelet rich plasma for the treatment of foot and ankle pathologies</title>
      <link>https://escholarship.org/uc/item/59c9653m</link>
      <description>Platelet rich plasma (PRP) is a concentrate of platelets and their bioactive factors derived from the peripheral venous blood of patients. Platelets contain factors that improve healing and tissue regeneration. PRP may offer an excellent means of non-operatively treating foot and ankle pathology. Objectives: to determine whether PRP injections improve outcomes for foot and ankle pathologies. Methods: A retrospective cohort study of patients aged ≥ 18 years diagnosed with foot or ankle pathology at University of California San Diego between January 2011 and September 2016 was performed. Patients treated with an intra-articular injection using platelet-rich plasma were categorized into the PRP group. Age and gender matching were used to select active comparator group (triamcinolone injection), and a control group (conservative treatment). Primary outcomes were patient-reported pain and function before treatment and at 12 weeks post-treatment. Pain ranged from 1-10 with higher scores...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/59c9653m</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Paul, S.</name>
      </author>
      <author>
        <name>Ahmed, S.</name>
      </author>
      <author>
        <name>Parekh, J.</name>
      </author>
    </item>
    <item>
      <title>ISP final project: adolescent medicine educational module</title>
      <link>https://escholarship.org/uc/item/5025j5pd</link>
      <description>&lt;p&gt;Project Objectives: The module serves to educate medical students and interns in completing an appropriate adolescent history and physical, and addresses many common topics practitioners will face with adolescent patients. It allows the students to work through case specific scenarios, as well as, review a typical adolescent visit filled with day-to-day clinical pearls and general practice guidelines. One module covers general health maintenance, differentiating normal vs. abnormal growth and development with emphasis on menstruation, as well as, routine screening to utilize and apply during an adolescent visit. The other module focuses on clinical descriptions and discussion of management for common adolescent issues including STIs, contraception, substance use, eating disorders, acne and obesity. The modules were created to give UCSD medical students and interns a platform of knowledge and an abundance of resources to efficiently and effectively provide care for their adolescent...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/5025j5pd</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Byrnes-Finger, Iris</name>
      </author>
    </item>
    <item>
      <title>Transitioning Medi-Cal eligible patients from the UCSD student-run free clinic project to community health centers in the context of the affordable care act</title>
      <link>https://escholarship.org/uc/item/4z0974gt</link>
      <description>The Affordable Care Act was implemented in 2014 and had a significant impact on the affordability and accessibility of healthcare for medically underserved populations within the United States. The UCSD Student-Run Free Clinic provides free and comprehensive medical care to underserved patients in San Diego County. The Free Clinic prioritizes providing healthcare to uninsured patients. Some Free Clinic patients gained insurance through the Affordable Care Act, and a subset of these insured patients continue to be cared for at the Free Clinic. Literature review suggested that patient navigators would be useful in helping these patients utilize their insurance and transition care to new medical homes.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/4z0974gt</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Kaiser, Jacob</name>
      </author>
    </item>
    <item>
      <title>Patient-specific 3D models aid planning for triplane proximal femoral osteotomy in slipped capital femoral epiphysis</title>
      <link>https://escholarship.org/uc/item/4w05905f</link>
      <description>Patient-specific 3D models aid planning for triplane proximal femoral osteotomy in slipped capital femoral epiphysis</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/4w05905f</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Upasani, V. V.</name>
      </author>
    </item>
    <item>
      <title>Cross cultural care : intersection of Eastern and Western medicine in the Chinese healthcare system</title>
      <link>https://escholarship.org/uc/item/4q5189fn</link>
      <description>On December 1st, I began the first day in a four week clerkship at Xuanwu Hospital (宣武医院) in Beijing, in the People's Republic of China. My original goals at the beginning of the clerkship were to: 1) gain an understanding of the healthcare system in the PRC; 2) observe their methods of balancing traditional remedies with evidence based methods; 3) further my knowledge of the Chinese language, with a focus on medical terminology. As this project encompassed "boots on the ground" experience wit hmyself as a primary source, I would like to preface this paper with the statement that all statements made are based off of my own observations, and whatever knowledge was passed to me by the healthcare providers that I interfaced with. Statistics are provided where appropriate, however this paper is meant to be subjective in nature, as a primary source for information regarding first hand interaction with the system.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/4q5189fn</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Qin, Mack Y.</name>
      </author>
    </item>
    <item>
      <title>Streamlining neuroanatomy : a video guided tour of the nervous system by Abd-Elrahman Hassan</title>
      <link>https://escholarship.org/uc/item/4kp963vv</link>
      <description>As the use of technology continues to increase in medical education, the utilization of video as a modality becomes apparent. This study is aimed at investigating the addition of video-guided anatomical discussions for the Mind, Brain and Behavior I (MBBI) course and its impact on student performance, specifically in the lab component, but also in the course as a whole. A series of videos were created that outlined a framework for how to approach neuroanatomy and then were provided on an online portal. An online survey was also provided to be used to assess use and provide a space for students to comment on the videos. Two successive classes (class of 2019 and 2020) were included in the data acquisition and analysis and compared with the class of 2018 (for which no videos existed). Performance was based on the mean score of each exam. "The class of 2020 (who had access to the videos) significantly outperformed the class of 2018 on the midterm and final (mean 85.0 +/- SD 11.1 vs....</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/4kp963vv</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Hassan, Abd-elrahman</name>
      </author>
    </item>
    <item>
      <title>University of California, San Diego LMSA/SNMA mock multiple-mini interviews (MMI) for underrepresented minority pre-medical students: findings about preparing historically under-represented students for medical school</title>
      <link>https://escholarship.org/uc/item/4gx661mj</link>
      <description>Underrepresented minority students, non-traditional students, and low-income students are important in strengthening and diversifying the physician workforce. Many universities across the nation have developed pipeline programs and community outreach events in efforts to increase minority student representation in medical education. University of California, San Diego School of Medicine Latino Medical Student Association (LMSA) and Student National Medical Associations (SNMA) chapters hosted an annual Mock Multiple Mini Interview (MMI) to help current and future medical school applicants, particularly non-traditional applicants, underrepresented minorities, and students from disadvantaged backgrounds by simulating a multiple-mini interview experience of the medical school admissions process. Participants had the opportunity to practice their MMI skills then receive feedback in efforts to improve these skills prior to medical school interviews. The Mock MMI event also included...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/4gx661mj</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Wilkins y Martinez, Lizett</name>
      </author>
      <author>
        <name>Burton, Brittany</name>
      </author>
      <author>
        <name>Garcia, Katherine</name>
      </author>
      <author>
        <name>Willies-Jacobo, Linda</name>
      </author>
    </item>
    <item>
      <title>Use of the GALAD score for serological prediction of hepatocellular carcinoma</title>
      <link>https://escholarship.org/uc/item/3rk9f43k</link>
      <description>Hepatocellular carcinoma (HCC) continues to be one of the leading causes of death among cancer patients worldwide. HCC occurs in well-defined at-risk populations, with curative therapy possible only for small tumors, making it a potential target for creating new screening techniques. Imaging in conjunction with serum biomarker measurements have been the hallmark of HCC diagnosis, but have shown limited use as a surveillance tool. An objective, GALAD score is a serum biomarker-based statistical model that predicts the probability of having HCC in patients with chronic liver disease. Consisting of gender, age, AFP, AFP-L3, and des-[gamma]-carboxyprothrombin (DCP), the GALAD model improves upon prior biomarker measurements by analyzing an AFP glycoform more specific to malignant tumors and HCC inflammation, and a prothrombin precursor able to differentiate HCC from non-malignant liver disease. This retrospective study is focused on validating the use of the GALAD model as a potential...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/3rk9f43k</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Nomura, Scott</name>
      </author>
    </item>
    <item>
      <title>Who's asking? Improving pediatric subspecialty clinic food insecurity screening</title>
      <link>https://escholarship.org/uc/item/3n12368n</link>
      <description>Food insecurity is associated with worse health, education, and socioeconomic status. In 2015, United States Department of Agriculture (USDA) reported 3 million households with children were food insecure. The USDA defines food insecurity as "the limited or uncertain availability of nutritionally adequate and safe foods." A recent American Academy of Pediatrics policy statement advised food insecurity screening for children. While this is embraced by primary care, locally we identified a gap in screening by subspecialty practice and aimed to address this in one pediatric subspecialty clinic within a busy tertiary referral center.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/3n12368n</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Vu, Michael</name>
      </author>
      <author>
        <name>Ruiz, Jen</name>
      </author>
      <author>
        <name>Pierce, Heather</name>
      </author>
      <author>
        <name>Glynn, Marcus</name>
      </author>
      <author>
        <name>Gottschalk, Michael</name>
      </author>
      <author>
        <name>Fisher, Erin S.</name>
      </author>
    </item>
    <item>
      <title>Streamlining management of distal forearm buckle fractures in a pediatric emergency department</title>
      <link>https://escholarship.org/uc/item/3h9846cq</link>
      <description>Distal forearm buckle fractures are common, inherently stable pediatric fractures. Immobilization, achieved with a removable splint is better tolerated, cheaper, and more efficient than cast treatment without increasing rates of re-fracture. Our children's hospital emergency department (ED) had no standardized protocol for the management of these fractures, resulting in varied immobilization methods, orthopedic consultations in the ED, and long lengths of stay.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/3h9846cq</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Konecny, Christina M.</name>
      </author>
      <author>
        <name>Dermartinis, Nicole C.</name>
      </author>
      <author>
        <name>Pring, Maya E.</name>
      </author>
      <author>
        <name>Shah, Seema</name>
      </author>
      <author>
        <name>Bryl, Amy W.</name>
      </author>
    </item>
    <item>
      <title>Bone metastatic prostate cancer : an overview of cell signaling, novel cell culture environment, and a push for cross-investigator collaboration</title>
      <link>https://escholarship.org/uc/item/3h34q34x</link>
      <description>Prostate cancer (CaP) continues to be the second leading causes of male cancer mortality in the United States despite our efforts to mitigate the cancer via better screening techniques and cancer management. Due to clinical advancements more men are diagnosed at an earlier, organ-confined, stage of prostate cancer decreasing the rate of metastatic disease to 4%. Nonetheless, metastatic disease is still a significant risk factor for those men who are not cured of the organ-confined disease. The treatment of recurrent prostate cancer usually consists of Androgen Deprivation Therapy (ADT), followed by chemotherapy and radiotherapy if the cancer becomes resistive and non-responding. Unfortunately, many bone metastasized prostate cancer cells become resistant to ADT and eventually leave no viable treatment options. Even more shocking is the fact that 100% of men who died of prostate cancer had bone metastases.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/3h34q34x</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Miakicheva, Olga</name>
      </author>
    </item>
    <item>
      <title>Independent study project : description and manuscript</title>
      <link>https://escholarship.org/uc/item/3f11858h</link>
      <description>Intrauterine devices are a reliable, long-term, and highly effective form of birth control that are becoming increasingly popular worldwide. As with many medical procedures, patients receiving an IUD may experience anxiety prior to the procedure. This mindset may actually be a self-fulfilling prophesy such that high expectations of pain produce increased discomfort. Currently, there is no proven method that reduces pain felt during IUD placement. It is unclear whether the expectation of pain is a significant predictor for discomfort felt during IUD placement, but results may provide insight as to how to better prepare patients mentally prior to the procedure.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/3f11858h</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Jimenez, Berenice</name>
      </author>
    </item>
    <item>
      <title>Unsuspected tarsal coalitions in congenital clubfoot and equinus</title>
      <link>https://escholarship.org/uc/item/37q4107r</link>
      <description>Tarsal coalitions have been reported to occur in the setting of clubfeet, but only as rare isolated findings. Other varus foot deformities have a known association with tarsal coalition, such as calcaneonavicular coalitions with spastic pes varus. The purpose of this paper was to report a two-institution count on the number of tarsal coalitions seen in congenital and neurogenic clubfeet, to report the break-down of types of coalitions encountered, and to suggest methodology to improve earlier diagnoses.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/37q4107r</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Van Rysselberghe, N.</name>
      </author>
    </item>
    <item>
      <title>Neuron-targeted caveolin-1 improves motor function and preserves memory in mice subjected to brain trauma</title>
      <link>https://escholarship.org/uc/item/2v59s3sq</link>
      <description>Studies in vitro and in vivo demonstrate that membrane/lipid rafts (MLR) and caveolin (Cav) organize pro-growth receptors, and when over-expressed specifically in neurons, Cav-1 augments neuronal signaling and growth, and improves cognitive function in adult and aged mice. However, whether Cav-1 overexpression can preserve motor and cognitive function in the setting of brain trauma is unknown. Here, we engineered a neuron-targeted Cav-1 overexpressing transgenic (Tg) mouse (via synapsin promoter, SynCav1 Tg) and subjected it to a controlled cortical impact (CCI) model of brain trauma and measured biochemical, anatomical, and behavioral changes. SynCav1 Tg mice exhibited increased hippocampal expression of Cav-1 and MLR-localization of PSF-95, NMDAR, and TrkB. When subjectd to CCI, SynCav1 Tg mice demonstrated preserved hippocampal-dependent fear learning and memory, motor function recovery on inverted grid, and decreased brain lesion volume. Conclusion: Neuron-targeted overexpression...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/2v59s3sq</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Posadas, Edmund</name>
      </author>
      <author>
        <name>Egawa, Junji</name>
      </author>
      <author>
        <name>Schilling, Jan M.</name>
      </author>
      <author>
        <name>Cui, Weihua</name>
      </author>
      <author>
        <name>Sawadi, Atsushi</name>
      </author>
      <author>
        <name>Alas, Basheer</name>
      </author>
      <author>
        <name>Zemljic-Harpf, Alice E.</name>
      </author>
      <author>
        <name>Fallon, McKenzie</name>
      </author>
      <author>
        <name>Mandyam, Chitra D.</name>
      </author>
      <author>
        <name>Roth, David M.</name>
      </author>
      <author>
        <name>Patel, Hemal H.</name>
      </author>
      <author>
        <name>Patel, Piyush M.</name>
      </author>
      <author>
        <name>Head, Brian P.</name>
      </author>
    </item>
    <item>
      <title>San Diego homeless hygiene evaluation</title>
      <link>https://escholarship.org/uc/item/2p71p7j2</link>
      <description>This focused clinical multidisciplinary independent study project (ISP) was designed to improve my understanding in the area of homeless hygiene challenges through a range of clinical and non-clinincal experiences. The project focused on the following goals: 1) Gain an understanding of the scope and impact of hygiene problems faced by the homeless population, a) appreciate the social, financial, and health impacts of homeless hygiene problems; 2) understand homeless hygiene problems from the different perspectives of the various stakeholders in the San Diego community; 3) understand the prioritization of hygiene problems from the perspectives of different community stakeholders; 4) gain insight into the reasons for the successes and failures of prior and current interventions; 5) learn about the acceptance or rejection of different types of interventions by various stakeholders in the community; 6) gain knowledge about the network of charitable programs and resources currently...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/2p71p7j2</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Williams, Brandon</name>
      </author>
    </item>
    <item>
      <title>Part 1: Hotspotting in the UCSD Student-Run Free Clinic: identifying patients for enrollment in Complex Care Service case management ; Part 2: Hotspotting applied: creating a model for the provision of case managed care for complex patients identified at the Student-Run Free Clinic Project</title>
      <link>https://escholarship.org/uc/item/2nh5z35x</link>
      <description>Part 1: The University of California, San Diego (UCSD) Student-Run Free Clinic Project (SRFCP) serves a subset of complex patients who may benefit from additional levels of care coordination and support beyond the scope of what is currently provided in the clinic. The Complex Care Service (CCS) created a patient-centered care delivery system featuring medical students as case managers to address the needs of this population. A student-run elective (FPM 275) that developed from the CCS is seekign to enroll complex patients that would benefit from coordinated case managed care. Complex patients must first be identified. This project examines current practices of patient identification through 'hotspotting', finding that most selection is through subjective physican referrals or objective emergency medical services (EMS) utilization data. It then uses these heuristics as a guide to systematically rank free clinic patients by complexity and healthcare utilization, finding that SRFCP...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/2nh5z35x</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Rule, Oresta</name>
      </author>
    </item>
    <item>
      <title>Metered-dose inhaler instruction : outpatient provider perspectives</title>
      <link>https://escholarship.org/uc/item/2js518j3</link>
      <description>How effectively do physicians teach patients to manage disease? 28-68% of patients do not use MDI effectively enough to benefit from prescribed medication; skills in inhaler use fatigue over time; 2007 NHLBI recommendations: teach and reinforce MDI skills at every visit and provider should demonstrate inhaler technique, have patient return the demonstration, and give feedback; 5.3% of providers demonstrated MDI technique at every visit and 13.3% assessed patient technique at every visit. Objectives: among San Diego county outpatient pediatric practices 1) identify what instructional methods are used to teach MDI use and who performs this teaching; 2) describe how MDI use is reassessed at follow up visits; 3) describe provider attitudes toward and barriers to in-office MDI instruction.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/2js518j3</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Schmitz, Dan</name>
      </author>
    </item>
    <item>
      <title>A medial portal for hip arthroscopy in children with septic arthritis : a safety study</title>
      <link>https://escholarship.org/uc/item/27w6m9w0</link>
      <description>Prompt open arthrotomy is historically utilized to treat pediatric septic arthritis of the hip, but arthroscopy has been described as a valid alternative to prevent long-term sequelae. Standard hip arthroscopy in adolescents and adults utilizes lateral-based portals, but successful irrigation in infants may necessitate a medial portal due to the smaller joint size. The purpose of this study was to determine the safety of a medial hip portal in children based on its anatomic relation to neurovascular structures.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/27w6m9w0</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Lin, Christina</name>
      </author>
      <author>
        <name>Edmonds, Eric W.</name>
      </author>
      <author>
        <name>Farnsworth, Christine L.</name>
      </author>
      <author>
        <name>Bomar, James D.</name>
      </author>
      <author>
        <name>Upsani, Vidyadhar V.</name>
      </author>
    </item>
    <item>
      <title>Economic impact of palliative care among elderly cancer patients</title>
      <link>https://escholarship.org/uc/item/227055sc</link>
      <description>Randomized trials among advanced cancer patients demonstrate that early palliative care integration into usual oncology care reduces symptom burden, improves quality of life and caregiver outcomes, and may improve survival. The impact of palliative care on health economics remains poorly defined and reported cost savings are an unintentional consequence of providing care aligned with patient goals. This study determined the impact of palliative care on healthcare costs among elderly patients with advanced cancer.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/227055sc</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>LeBrett, Wendi</name>
      </author>
    </item>
    <item>
      <title>Dried blood spots as a tool for measuring ovarian reserve in young female cancer survivors</title>
      <link>https://escholarship.org/uc/item/1mp5f23v</link>
      <description>More than 80% of women who are diagnosed with cancer before the age of 40 will survive long-term. As a result, there are nearly 400,000 reproductive-aged women who have a history of cancer and cancer treatment in the United States. Due to cancer treatment, these young cancer survivors face higher risks for shortened reproductive lifespans, infertility, and primary ovarian insufficiency. Therefore, estimating their remaining ovarian reserve is important to identify potential opportunities for biologic parenthood. Anti-mullerian hormone (AMH) is a glycoprotein produced by early staged ovarian follicles in women and can be used as a sensitive biomarker of ovarian reserve. It has been shown that pre-chemotherapy AMH levels can predicts post-chemotherapy ovarian function, making AMH a promising clinical tool for measuring residual ovarian function after cancer. However, logistics and costs fo venipuncture blood collection associated with AMH testing have limited our ability to further...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/1mp5f23v</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Seav, Susan</name>
      </author>
    </item>
    <item>
      <title>Confocal Scanning Laser Ophthalmoscopy (CSLO)-based Topographic Change Analysis in progressing glaucomatous and stable eyes</title>
      <link>https://escholarship.org/uc/item/1jg977hf</link>
      <description>To assess the performance, in an independent population, of previously published confocal scanning laser ophthalmoscopy Topographic Change Analysis (TCA) parameter cut-offs ofr discriminating between progressing glaucoma, stable glaucoma, and healthy eyes. Five published TCA cut-offs were applied to the following four groups: 54 glaucomatous eyes (at study baseline examination) progressing by optic disc stereophotograph assessment, 79 glaucomatous eyes progressing by standard automated perimetry guided progression analysis (GPA), 72 stable glaucoma eyes (patients tested 5 times over 5 weeks), and 135 healthy eyes. All eyes were imaged at least four times by Heidelberg Retina Tomograph (HRT; Heidelberg Engineering, Heidelberg, Germany) as part of the Diagnostic Innovations in Glaucoma Study (DIGS) and African Descent and Glaucoma Evaluation Study (ADAGES). Sensitivity and specificity for classifying progressed and stable eyes, respectively, were reported. The two TCA parameters...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/1jg977hf</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Nayak, Jagannath Sam</name>
      </author>
    </item>
    <item>
      <title>Cardiac arrest and helicopter emergency medical transports : an analysis of 10,200 cardiac arrest patients transported by helicopter emergency medical services (HEMS) in the United States from 2004 to 2011</title>
      <link>https://escholarship.org/uc/item/1gp701j9</link>
      <description>This study was a structured review of existing electronic clinical and logistical records of HEMS transports created using the International Classification of Disease, Ninth Edition (ICD-9) and other diagnostic identifiers. Data were collected during HEMS patient documentation within integrated software from Golden Hour Data Systems, Inc (San Diego, CA) using an information management service that integrates clinical and dispatch data on "cloud-based" servers managed by the electronic medical recrod (EMR) providers. Data are owned by the HEMS provider. All providers agreed contractually to a deidentified data sharing protocol through the EMR provider, permitting academic research. The entire anonymous database spanned the years 2004 through 2011 and consisted of 861,284 HEMS transports. Cardiac arrests were identified by ICD-9 codes, ICD-9 text and text entry "reason for transport" inputs with the assistance of a certified medical coder. Fixed wing and ground transports were excluded....</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/1gp701j9</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Shine, Ryan</name>
      </author>
    </item>
    <item>
      <title>Effects of enrollment in a student-run free clinic elective on third year clerkship evaluations and grades</title>
      <link>https://escholarship.org/uc/item/1dz409pd</link>
      <description>We retrospectively examined the association between enrollment in the student-run free clinic elective and University of California-San Diego (UCSD) medical student performance on third-year clinical rotations between 2012 and 2017. Free clinic participation was examined both as a binary variable and based on the total number of units taken (2, 4, and &amp;gt;4). Student performance was assessed using a standardized evaluation rubric that included the following seven categories for every rotation: medical knowledge (MK), clinical reasoning (CR), data gathering skills (DGS), communication of clinical data and medical information (CCD), interpersonal communication skills and humanisitc qualities (ICS), professionalism (PRO), and potential as a resident in the discipline (POT). Evaluation scores were analyzed individually and as a composite score across each rotation discipline as well as chronologicall over the school year. We found that enrollment in the free clinic elective had statistically...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/1dz409pd</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Martinez, Armando</name>
      </author>
    </item>
    <item>
      <title>Accuracy of magnitude- and complex-reconstruction chemical-shift-encoded magnetic resonance imaging proton density fat fraction for diagnosis of hepatic steatosis in subjects with severe obesity using histology as reference</title>
      <link>https://escholarship.org/uc/item/15j3633x</link>
      <description>To assess and compare the diagnostic performance of magnitude-reconstruction chemical-shift-encoded magnetic resonance imaging (MRI-M) and complex-reconstruction chemical-shift-encoded magnetic resonance imaging (MRI-C) for diagnosis of hepatic steatosis in subjects with severe obesity without known non-alcoholic fatty liver disease (NAFLD), using contemporaneous histology as reference. This is an IRB-approved, HIPAA-compliant, two-center, cross-sectional study of a larger prospective trail that recruited patients without known NAFLD consecutively between October 2010 and March 2015 to undergo research MRI exams 1-2 days prior to clinical-care weight-loss surgery. Proton denisty fat fraction (PDFF) was estimated using MRI-M and MRI-C. Liver biopsies were obtained intraoperatively. Using histologically-determined presence of steatosis as the reference standard, receiver operating characteristics (ROC) analyses were used to identify MRI-M- and MRI-C-derived PDFF thresholds for diagnosing...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/15j3633x</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Thai, Tydus T.</name>
      </author>
      <author>
        <name>Hamilton, Gavin</name>
      </author>
      <author>
        <name>Covarrubias, Yesenia</name>
      </author>
      <author>
        <name>Hooker, Jonathan C.</name>
      </author>
      <author>
        <name>Schlein, Alex N.</name>
      </author>
      <author>
        <name>Middleton, Michael S.</name>
      </author>
      <author>
        <name>Ballanay, Michelle L.</name>
      </author>
      <author>
        <name>Haufe, William M.</name>
      </author>
      <author>
        <name>Wiens, Curtis N.</name>
      </author>
      <author>
        <name>Artz, Nathan S.</name>
      </author>
      <author>
        <name>Funk, Luke M.</name>
      </author>
      <author>
        <name>McMillan, Alan</name>
      </author>
      <author>
        <name>Agni, Rashmi</name>
      </author>
      <author>
        <name>Peterson, Michael</name>
      </author>
      <author>
        <name>Campos, Guilherme M.</name>
      </author>
      <author>
        <name>Greenberg, Jacob</name>
      </author>
      <author>
        <name>Horgan, Santiago</name>
      </author>
      <author>
        <name>Jacobson, Garth</name>
      </author>
      <author>
        <name>Wolfson, Tanya</name>
      </author>
      <author>
        <name>Gamst, Anthony</name>
      </author>
      <author>
        <name>Schwimmer, Jeffrey</name>
      </author>
      <author>
        <name>Reeder, Scott B.</name>
      </author>
      <author>
        <name>Sirlin, Claude B.</name>
      </author>
    </item>
    <item>
      <title>Physiological effects of a spit sock</title>
      <link>https://escholarship.org/uc/item/0xr1d56t</link>
      <description>Healthcare providers and law enforcement utilize spit socks to provide a direct method of universal precautions to prevent exposure to communicable diseases transmitted by bodily fluid projection from an agitated or altered individual. There are cases in which death of an individual is reported in part to have occurred from adequate breathing being limited or reduced by use of a spit sock. There are no formally published studies on the use and safety of spit socks in the medical literature. The aim of this study was to evaluate whether there is a clinically significant impact on breathing and ventilation in subjects with a protective spit sock placed on their head. This prospective study evaluated the effect of spit sock application on vital signs and ventilatory parameters of health adult volunteers, compared to baseline parameters without the spit sock. The subjects were placed on a chair and baseline vital signs and ventilatory parameters were taken, including heart rate, oxygen...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/0xr1d56t</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Lutz, Marie</name>
      </author>
      <author>
        <name>Sloane, Christian</name>
      </author>
      <author>
        <name>Castillo, Edward M.</name>
      </author>
      <author>
        <name>Brennan, Jesse</name>
      </author>
      <author>
        <name>Coyne, Christopher J.</name>
      </author>
      <author>
        <name>Vilke, Gary M.</name>
      </author>
    </item>
    <item>
      <title>Liable : experiences and views on medical malpractice among OBGYNs and UCSD, a working paper</title>
      <link>https://escholarship.org/uc/item/0vs1b3bk</link>
      <description>The purpose of this project is to cut a window in the opaque edifice of medical liability for young and aspiring OBGYNs to peer through. In addition to reviewing a wealth of literature on medical liability, I interviewed a diverse collection of OBGYNs at UCSD about their experiences with and views of medical malpractice. By integrating these narratives with the literature. This paper attempts to capture three perspectives that, I hope, offer greater texture and deeper understanding to young clinicians trying to make sense of medical liability: 1) What it feels like to be sued and the challenges associated with coping on the job; 2) What advice physicians have to avoid being sued (and a note on attorneys); 3) Where our system of medical liability falls short and how it might be improved.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/0vs1b3bk</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Stone, Jordan S.</name>
      </author>
    </item>
    <item>
      <title>Medical spanish proficiency as an independent study project</title>
      <link>https://escholarship.org/uc/item/0rx965qq</link>
      <description>As part of a focused, clinical, multi-disciplinary, independent study project, the author of this paper, a fourth-year medical student, completed a rigorous, six-month, longitudinal study of Medical Spanish for the purpose of improving his Medical Spanish proficiency. To accomplish this goal, an independent study plan was developed which included advancing-level Medical Spanish coursework, clinical practicum in Medical Spanish, and formal assessment of Spanish proficiency. An NIH supported Medical Spanish course offered by Canopy Innovations was completed from the beginner through advanced levels. Tests at each course level are offered by Canopy and were passed before continuing on to successive levels. Clinical practicum was completed in vivo with Spanish-speaking patients throughout the student's clinical rotations. Spanish proficiency was assessed as part of this project through independent, third-party agencies specializing in language assessment. Student Spanish proficiency...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/0rx965qq</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Guerrero, Hector</name>
      </author>
    </item>
    <item>
      <title>The potential anti-microbial use of azithromycin against multi-drug resistant Burkholderia cepacia complex in cystic fibrosis patients</title>
      <link>https://escholarship.org/uc/item/0k93p54r</link>
      <description>Cystic Fibrosis (CF) is an autosomal recessive disease that affects thousands of individuals worldwide. The disease is caused by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene resulting in the dysregulation of apical ion channels. This disruption in ion transport leads to the production of the characteristic thick mucus seen in patients with CF. Although many organ systems are affected, the hallmark of the disease is viscous mucous plugs in the respiratory tracts leading to the disruption of mucociliary clearance and chronic bacterial colonization of the airways. Infections by organisms of the &lt;em&gt;Burkholderia cepacia&lt;/em&gt; complex (BCC), a group of about 17 closely related species of Gram-negative bacteria, are associated with fulminant necrotizing pneumonia and severe decline in CF lung function. Acute exacerbations of CF are treated rapidly with antibiotics to halt further destruction of the lung. This repeating antibiotic exposure, however,...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/0k93p54r</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Khoury, Amanda</name>
      </author>
    </item>
    <item>
      <title>NG tube and catheter manikin simulation : an expansion of practical curriculum</title>
      <link>https://escholarship.org/uc/item/0bx8j7n5</link>
      <description>This medical education project sought to expand practical training at UCSD, School of Medicine. Specifically this was envisioned through creation of novel nasogastric intubation and urinary catheterization curriculum. Prior to the conception of this project, UCSD employed a wide range of simulated procedures for instructional use during the pre-clinical and clinical years: endotracheal intubation, central lines, arterial lines, etc. Anecdotally, these sessions were helpful for familiarization with the equipment and procedures that I would commonly encounter on the wards during my third and fourth years. Using these ideas as a framework, I planned to develop sessions to cover additional topics that I encountered in my clinical rotations but not in the classroom. Foley catheterization and nasogastric intubation were specifically chosen as they are both extremely common procedures.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/0bx8j7n5</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Wood, Samuel</name>
      </author>
    </item>
    <item>
      <title>Long-term mode and timing of premature ventricular complex recurrence following successful catheter ablation</title>
      <link>https://escholarship.org/uc/item/07g3h0fc</link>
      <description>Catheter ablation of PVCs is highly successful and has become the hallmark treatment for symptomatic or highly prevalent cases. However, few studies exist that evaluate the outcomes of ablation and likely mechanisms of PVC recurrence beyond 1 year of follow-up.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/07g3h0fc</guid>
      <pubDate>Tue, 21 May 2019 00:00:00 +0000</pubDate>
      <author>
        <name>Lee, Derek</name>
      </author>
      <author>
        <name>Hoffmayer, Kurt S.</name>
      </author>
      <author>
        <name>Hsu, Jonathan C.</name>
      </author>
      <author>
        <name>Schricker, Amir</name>
      </author>
      <author>
        <name>Birgersdotter-Green, Ulrika</name>
      </author>
      <author>
        <name>Raissi, Farshad</name>
      </author>
      <author>
        <name>Feld, Gregory K.</name>
      </author>
      <author>
        <name>Krummen, David E.</name>
      </author>
    </item>
    <item>
      <title>Influence of Age, Race and Image Quality on Spectral Domain Optical Coherence Tomography (SDOCT) based measures of the Ganglion Cell Layer (GCL), Macular Thickness (MT), Retinal Nerve Fiber Layer (RNFL) and Neuroretinal Rim Area in healthy adult eyes.</title>
      <link>https://escholarship.org/uc/item/9nf2z2h9</link>
      <description>In this cross-sectional study of healthy participants, age was inversely associated with GCL, macular, and RNFL thickness regardless of race. Clinicians should consider the associations between age, RNFL, and GCL thickness to help differentiate between aging-related changes and glaucomatous progression.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/9nf2z2h9</guid>
      <pubDate>Thu, 20 Sep 2018 00:00:00 +0000</pubDate>
      <author>
        <name>Rungvivatjarus, Tiranun</name>
      </author>
    </item>
    <item>
      <title>Computer-generated laryngoscopy profiles to assess competence in airway management.</title>
      <link>https://escholarship.org/uc/item/9f3562nm</link>
      <description>Background : A method to discern a trainee's expertise with direct laryngoscopy would be useful for following progress and determining readiness for call or advanced assignments. We have developed methodology to record laryngoscopy motion and performance. The goal of this study was to determine whether laryngoscopy skill could be evaluated by electronic assessment of technique. Methods : Three anesthesia faculty with three to 23 years experience performed laryngoscopy five times each on a Medical Plastics Intubation Mannequin. Blade path and force were measured with a Mini-Bird magnetic position sensor (Ascension) and a 6-axis force transducer (ATI), respectively, attached to the laryngoscope handle and recorded on a Dell laptop computer. A Matlab (Mathworks) program digitally aligned the separate laryngoscopy trajectories and a virtual curvilinear tube was calculated within the mannequin airway that encompassed all the expert trajectories. Twelve residents were studied on the...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/9f3562nm</guid>
      <pubDate>Thu, 20 Sep 2018 00:00:00 +0000</pubDate>
      <author>
        <name>Moitoza, Jennifer</name>
      </author>
    </item>
    <item>
      <title>Outcomes and Complications of Pediatric Acute Myelogenous Leukemia at Rady's Children's Hospital San Diego : a Retrospective Study.</title>
      <link>https://escholarship.org/uc/item/9cv471p3</link>
      <description>Background : While overall 5-year survival has improved by approximately 50% in pediatric AML patients in the last twenty years with intensification of antineoplastic therapy and advancement in antimicrobial therapy, treatment-related complications continue to be a major problem. Prior studies have demonstrated that mandatory hospitalization during profound neutropenia did not reduce infections or significantly reduce nonrelapse mortality (NRM). The aim of this study was to evaluate the effect of our supportive care measures on treatment-related mortality (TRM), event free survival (EFS), and overall survival (OS). Secondary aims of this study were to document infectious complications of AML therapy, which organisms were isolated most frequently from blood cultures, quantify the number of antibiotic modifications made for each patient throughout treatment and observe how many patients were admitted to the pediatric intensive care unit (PICU) for septic shock and acute respiratory...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/9cv471p3</guid>
      <pubDate>Thu, 20 Sep 2018 00:00:00 +0000</pubDate>
      <author>
        <name>Koo, Jane</name>
      </author>
    </item>
    <item>
      <title>Creating an online quick-reference of neuropsychiatric drugs featuring a randomized quiz generator.</title>
      <link>https://escholarship.org/uc/item/9b54200m</link>
      <description>This project's main goals include 1) establishing a searchable online reference of common neuropsychiatric medications with a knowledge base at the level of 3rd-year medical students and 2) establishing a randomized interactive review system in the form of flashcards and quizzes. A minor goal was to ensure flexibility and modularity in the design so that additions or changes to the database can be easily and rapidly effected. Finally, personal goals include learning and first-hand experience in dynamic website design using the PHP language and MySQL database management.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/9b54200m</guid>
      <pubDate>Thu, 20 Sep 2018 00:00:00 +0000</pubDate>
      <author>
        <name>Guo, Yueyang</name>
      </author>
    </item>
    <item>
      <title>IL-33 and ST2 in Allergic Asthma.</title>
      <link>https://escholarship.org/uc/item/9b13b68n</link>
      <description>Although our understanding of the pathogenesis of asthma remains limited, data now indicate that most patients with asthma have an immune-mediated component. Allergic asthma is thought to involve a response to a specific antigen that triggers a specific adaptive immune response in the lung that requires time. However, new data also implicate the innate immune response, either in concert with or independent of the adaptive response. The broad goal of this project was to explore the role that the cytokine interleukin (IL) 33 and its receptor, ST2, may play in asthma. The first objective was to explore the role of ST2 in a mouse model of asthma in which ovalbumin is used to induce airway hyperresponsiveness and inflammation. We hypothesized that ovalbumin-challenged mice would show increased expression of ST2 compared to unchallenged mice. The second objective was to characterize the stimuli for expression and release of IL-33 from the human airway epithelium using the human airway...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/9b13b68n</guid>
      <pubDate>Thu, 20 Sep 2018 00:00:00 +0000</pubDate>
      <author>
        <name>Nguyen, Tammie</name>
      </author>
    </item>
    <item>
      <title>Chronic Opioids and Sleep Disordered Breathing.</title>
      <link>https://escholarship.org/uc/item/8z79t637</link>
      <description>Prescription opioid use for chronic pain has increased significantly in the past several decades, and an understanding of the risks associated with long term opioid use is important for the health of the patients. Past research has suggested a link between chronic opioid use and sleep apnea, which could have a significant effect on the morbidity and mortality of the chronic pain population. The goal of this study was to determine the prevalence of sleep apnea in the chronic pain population at the UCSD Center for Pain Medicine and Palliative Care Clinic, and to determine whether treatment of sleep apnea in patients with chronic pain has an positive effect on their pain levels.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/8z79t637</guid>
      <pubDate>Thu, 20 Sep 2018 00:00:00 +0000</pubDate>
      <author>
        <name>King, Brian</name>
      </author>
    </item>
    <item>
      <title>Allelic effects of RAS, BRAF and MEK on hair morphology.</title>
      <link>https://escholarship.org/uc/item/8xs5w6fj</link>
      <description>The effects of activating mutations in HRAS, BRAF, and MEK1 were examined on human hair. We found that all three mutations induced a tightly curled morphology. Histologic and scanning electron microscopy analysis revealed the tightly curled phenotype of cardiofaciocutaneous syndrome hair to be indistinguishable from normal tightly curled hair. No differences were detected in Costello syndrome hair compared to normal tightly curled hair, except for greater variety of cross sectional shape; however, this analysis was limited to a single sample. These findings suggest that the normal curled phenotype of human hair could be caused by increased RAS/RAF signaling. Although the alleles of RAS/MAPK syndrome patients vary in strength, curly hair development may respond after a signaling threshold is reached. It may be possible to predict specific phenotypes in humans experiencing excess or insufficient RAS/RAF signaling. Further efforts are ongoing to identify whether there are normal...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/8xs5w6fj</guid>
      <pubDate>Thu, 20 Sep 2018 00:00:00 +0000</pubDate>
      <author>
        <name>Burns, Julianne</name>
      </author>
    </item>
    <item>
      <title>Differences in gene expression between young and adult mice may play a protective role against insulin resistance in the setting of high fat diet-induced obesity.</title>
      <link>https://escholarship.org/uc/item/8vv074k3</link>
      <description>As the prevalence of childhood obesity increases in the United States, the prevalence of obesity-related co-morbidities, such as type 2 diabetes mellitus, has increased as well. However, there is currently limited published data on the role of genes and signaling pathways in childhood obesity. Obesity is described as a cause of type 2 diabetes mellitus mediated by chronic inflammation. Our goal is to determine the role of genes in adipose tissue in insulin resistance amongst young pubertal mice by investigating the gene expression profiles of young and adult murine adipose tissue in diet-induced obesity. In our study, we hypothesized that adipose tissue gene profiles differ between young and adult mouse populations. To investigate these differences in adipose tissue between young and adult mice, we utilized genome-wide transcriptional microarray analysis. Results from this study showed that adult mice on high fat diet (HFD) have increased fat mass in comparison to their age-matched...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/8vv074k3</guid>
      <pubDate>Thu, 20 Sep 2018 00:00:00 +0000</pubDate>
      <author>
        <name>Koo, Jenny</name>
      </author>
    </item>
    <item>
      <title>Implicit attitudes of health care providers and their effect on racial and socioeconomic equality.</title>
      <link>https://escholarship.org/uc/item/8t84j7p4</link>
      <description>Our study uses two survey instruments to measure the explicit and implicit attitudes of medical and pharmacy students regarding issues of culture and race. The surveys are designed to assess which aspects of cultural competency are the most challenging for health professional students, as well as to measure their subconscious attitudes towards people of different races. The data from this project is valuable in two ways. It replicates the work of White-Means et al. (2009) in a different region of the U.S., thereby advancing our understanding of how the diverse social context of Southern California impacts cultural competency and provider attitudes as compared to other regions of the country. Additionally, it provides a baseline assessment to aid in the implementation and evaluation of cultural competency curriculum that is tailored to our population of students. Our research shows a high prevalence of implicit racial bias among health professional students. This project is relevant...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/8t84j7p4</guid>
      <pubDate>Thu, 20 Sep 2018 00:00:00 +0000</pubDate>
      <author>
        <name>Rich, Nicole</name>
      </author>
    </item>
    <item>
      <title>Relationship Between Depression and Clinical Outcomes of BMI, Diabetes, Blood Pressure and LDL in Diabetic Patients at the UCSD Student-Run Free Clinic Project and UCSD Department of Family Medicine Clinics.</title>
      <link>https://escholarship.org/uc/item/8q09p75t</link>
      <description>Depression is a common condition often addressed in the outpatient setting. Patients with chronic medical illnesses, including diabetes, have a two to four fold increase in rates of depression. Those with diabetes and depression have higher rates of cardiovascular risk factors, noncompliance and health care expenditure. We completed a cross-sectional analysis of prevalence and characteristics of diabetic patients with and without depression at two distinct clinical settings, the UCSD Student Run Free Clinic Project (UCSD SRFCP) and UCSD Family Medicine clinics (UCSD FM). We also analyzed specific clinical measures (BMI, LDL, blood pressure) and their relationship to a depression diagnosis in those with comorbid diabetes. Each clinic setting serves different and specific populations however depression prevalence at both sites was similar to previously studied values, 23-26%. Rates of diabetes complications, including nephropathy, neuropathy, retinopathy and myocardial infarction...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/8q09p75t</guid>
      <pubDate>Thu, 20 Sep 2018 00:00:00 +0000</pubDate>
      <author>
        <name>Manjunath, Rashmi</name>
      </author>
    </item>
    <item>
      <title>The cutaneous microenvironement influences wound healing through toll-like receptor modulation of inflammation.</title>
      <link>https://escholarship.org/uc/item/8pr5d716</link>
      <description>Chronic wounds are a major source of morbidity in the United States, affecting an estimated 5.7 million people per year at a cost of 20 billion dollars annually. Underlying factors, such as diabetes, poor perfusion due to vascular disease, or infection, complicates many of these wounds. The normal wound healing process proceeds through three stages, which are precisely choreographed. Appropriate early inflammation is required to sterilize and debride the wound, followed by an orderly transition to repair processes. Inappropriate inflammation can result in pathologic wound healing. It is well recognized that the commensal organisms present in the gut play an important role in mediating gastrointestinal immunity and inflammatory responses through their interaction with innate pathogen recognition receptors, such as TLRs. The skin is also continuously exposed to potential pathogens and possesses unique microflora. Recently, the common cutaneous commensal, Staphylococcus epidermidis,...</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/8pr5d716</guid>
      <pubDate>Thu, 20 Sep 2018 00:00:00 +0000</pubDate>
      <author>
        <name>Dorschner, Robert Anthony</name>
      </author>
    </item>
    <item>
      <title>Etiology of in-hospital cardiopulmonary arrest as a predictor of outcome.</title>
      <link>https://escholarship.org/uc/item/8h08438g</link>
      <description>Our comprehensive taxonomy categorizing cardiac arrests by etiology lead to interventions which may prevent arrests, informed conversations with patients and their surrogates in regard to outcome in the event of an arrest, and led to changes in resuscitation strategy (ventilations, defibrillation timing and pressor use) that contributed to improved surviva.</description>
      <guid isPermaLink="true">https://escholarship.org/uc/item/8h08438g</guid>
      <pubDate>Thu, 20 Sep 2018 00:00:00 +0000</pubDate>
      <author>
        <name>Gordon, James</name>
      </author>
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