Diagnosis of Inflammatory Bowel Disease Using a Robust 14 Species Signature

Fri, 17 Oct 2025 00:00:00 +0000

First Place Winner 2023 Life Sciences, Physical Sciences and Engineering Category, nominated by Weg M. Ongkeko (Department of Surgery).

Inflammatory bowel diseases (IBD) are disorders of the gastrointestinal system affecting a considerable portion of Western populations. With nearly 6.8 million individuals affected globally, the ability to accurately and efficiently diagnose the disease in patients is crucial. The gastrointestinal microbiome composition has been associated with several diseases, disorders, and cancers. Several microbial signature-based machine learning IBD predictive models have been developed but have yet to be implemented clinically due to poor external accuracy. This study analyzes the microbial compositions of 1612 stool samples from 665 patients across seven distinct shotgun metagenomic cohorts in constructing an IBD diagnostic model capable of high predictive accuracy and robustness. We created a 14-species diagnostic ML panel and validated the...

Seeking Justice: Limited Tribal Jurisdiction in Cases of Sexual Violence

Fri, 17 Oct 2025 00:00:00 +0000

First Place Winner 2023 Social Sciences, Arts and Humanities Category, nominated by Mary Klann (Department of History)

Using a hypothetical case, examines the legal options available to a Hopi woman raped by her non-Indian husband in the Hopi reservation in Coconino County, Arizona. The Hopi Tribal Government has no jurisdication over this crime and recommends filing either a Civil Protection Order or a Domestic Violence Restraining Order with the state of Arizona. The paper examines the pros and cons of either choice

Recent ucsd_libraries_ulrp_2023 items

Diagnosis of Inflammatory Bowel Disease Using a Robust 14 Species Signature

Seeking Justice: Limited Tribal Jurisdiction in Cases of Sexual Violence