Recent ucsd_libraries_ulrp_2022 items

The Immune Landscape of COVID-19 and Cardiovascular Disease

Fri, 17 Oct 2025 00:00:00 +0000

First Place Winner 2022, nominated by Weg M. Ongkeko (Department of Surgery)

Patients with cardiovascular disease display significant similarities with inflammation-related genes in COVID-19. Immune dysregulation provides specific explanations for increased COVID-19 disease severity. Coronary artery disease patients display the most similarity to COVID-19 immune landscape. Identifying immune targets vital to treating COVID-19 patients with CVD comorbidities.

Examining Instructor Conceptions of Diversity

Fri, 17 Oct 2025 00:00:00 +0000

First Place Winner 2022, nominated by Stanley Lo (Department of Cell and Developmental Biology)

The goal of this study is to develop a quantitative survey informed by education field research to examine the conceptions of diversity in a larger population of faculty across the nation. The results of this survey could serve as a reflection tool for instructors that would allow them to better understand their own conceptions of diversity. In doing this, we hope to increase instructors' awareness of their biases and perceptions of diversity in order to encourage conceptual change as well as positively promote equity and inclusive classrooms.

The Role of Gut Microbial Bile Acid Deconjugation on PCOS

Fri, 17 Oct 2025 00:00:00 +0000

Second Place Winner 2022, nominated by Amir Zarrinpar (Department of Gastroenterology)

Polycystic ovary syndrome is the leading cause of infertility and is often ineffectively treated. The LET mouse model replicates PCOS phenotype. Exposure to healthy gut microbiome ameliorates PCOS in mice. Gut microbes that express BSH can modify bile acids. BSH-expressing ENB facilitate bile acid deconjugation in mice. Mice with BSH-expressing ENB have improved insulin response. BSH does not affect normal mouse estrous cyclicity. Mice with BSH-expressing ENG have decreased androgen levels. BSH-expressing bacteria might have potential to prevent human PCOS.

Realizing 2D and 3D Single-Crystal Perovskite Devices

Fri, 17 Oct 2025 00:00:00 +0000

Second Place Winner 2022, nominated by Sheng Xu (Department of Nanoengineering)

Perovskites could be used for solar cells, LEDs, lasers, photodetectors and much more, but there are programs that need to be solved: their lifetime, efficiency, and toxicity. Examines the feasibility of making devices by growing single crystal perovskites.